1026504-57-3

Basic information

• Product Name: 2-(4-phenylpiperidin-1-yl)pyridine
• Synonyms: 2-(4-phenylpiperidin-1-yl)pyridine
• CAS NO: 1026504-57-3
• Molecular Weight: 238.332
• Mol File: 1026504-57-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-phenylpiperidin-1-yl)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-phenylpiperidin-1-yl)pyridine(1026504-57-3)
• EPA Substance Registry System: 2-(4-phenylpiperidin-1-yl)pyridine(1026504-57-3)

Safety Data

• Hazardous Substances Data: 1026504-57-3(Hazardous Substances Data)

Upstream product

• 771-99-3 4-phenylpiperidine 
• 874493-33-1 pyridin-2-yl N,N,N',N'-tetramethyldiamidophosphate 
• 142-08-5 2-hydroxypyridin 
• 372-48-5 2-fluoropyridine 
• 10272-49-8 4-phenylpiperidine hydrochloride 

Downstream Products

• 1401997-72-5 2-(2,6-dihexyl-4-phenylpiperidin-1-yl)pyridine 
• 1631043-20-3 cis/Cis-2-{2,6-bis[2-(2-methyl-1,3-dioxolan-2-yl)ethyl]-4-phenylpiperidin-1-yl}pyridine 
• 1631043-21-4 trans/trans-2-{2,6-bis[2-(2-methyl-1,3-dioxolan-2-yl)ethyl]-4-phenylpiperidin-1-yl}pyridine 

Relevant articles and documents

Amination of Phosphorodiamidate-Substituted Pyridines and Related N-Heterocycles with Magnesium Amides

The amination of various phosphorodiamidate-substituted pyridines, quinolines, and quinoxaline with magnesium amides R2NMgCl·LiCl proceeds at room temperature within 8 h. Several pharmaceutically active amines were suitable substrates for this amination procedure, and also the antihistaminic tripelennamine was prepared. Additionally, several heterocyclic phosphorodiamidates underwent directed ortho-metalation (DoM) using TMPMgCl·LiCl (TMP = 2,2,6,6-tetramethylpiperidyl) or TMP2Mg·2LiCl, followed by electrophilic functionalization prior to the amination step, which led to ortho-functionalized aminated N-heterocycles.