102653-68-9

Basic information

• Product Name: 3-BROMO-6-METHYLCHROMONE
• Synonyms: 3-BROMO-6-METHYL-4H-CHROMEN-4-ONE;3-BROMO-6-METHYLCHROMONE
• CAS NO: 102653-68-9
• Molecular Formula: C₁₀H₇BrO₂
• Molecular Weight: 239.07
• Product Categories: Chromones
• Mol File: 102653-68-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-BROMO-6-METHYLCHROMONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-6-METHYLCHROMONE(102653-68-9)
• EPA Substance Registry System: 3-BROMO-6-METHYLCHROMONE(102653-68-9)

Safety Data

• Hazardous Substances Data: 102653-68-9(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-Methylchromone is a chemical compound with the molecular formula C10H7BrO2. It is a derivative of chromone, which is a heterocyclic compound commonly found in plants. The addition of a bromine atom at the 3 position and a methyl group at the 6 position gives this compound unique chemical properties. 3-Bromo-6-Methylchromone is used in organic synthesis and pharmaceutical research, and it has shown potential as a drug candidate for treating various medical conditions. Its molecular structure and properties make it a valuable tool for chemical and biological studies.

Upstream product

• 110-89-4 piperidine 
• 60-29-7 diethyl ether 
• 103030-34-8 2,3-dibromo-6-methyl-chroman-4-one 
• 89807-39-6 1-(2-hydroxy-5-methylphenyl)-3-(N,N-dimethylamino)propenone 
• 107055-51-6 6-methyl-3-piperidino-chroman-4-one 
• 38445-23-7 6-methyl-chromen-4-one 

Downstream Products

• 1429426-05-0 2-(2-hydroxy-5-methylbenzoyl)-4H-furo[3,2-c]chromen-4-one 
• 1429426-07-2 2-(2-hydroxy-5-methylbenzoyl)-8-methyl-4H-furo[3,2-c]chromen-4-one 

Relevant articles and documents

Synthesis of functionalized 2-salicyloylfurans, furo[3,2-b]chromen-9-ones and 2-benzoyl-8H-thieno[2,3-b]indoles by one-pot cyclizations of 3-halochromones with β-ketoamides and 1,3-dihydroindole-2-thiones

Functionalized 2-salicyloylfurans and 2-benzoyl-8H-thieno[2,3-b]indoles were prepared under mild conditions by reaction of 3-halochromones with β-ketoamides and 1,3-dihydroindole-2-thiones, correspondently. The subsequent oxidative cyclization of the products resulted in formation of the corresponding furo[3,2-b]chromen-9-ones. These molecules could also be directly prepared from 3-halochromones using a one-pot protocol. The cyclization reactions reported herein are mechanistically surprising as they proceed via the oxygen and not via the (more nucleophilic) nitrogen atom of the β-ketoamide. This journal is

Synthesis of 3-halochromones with simple KX halogen sources enabled by: In situ halide oxidation

On the basis of a designated in situ oxidation tactic, the synthesis of 3-halochromones has been realized for the first time by using simple KX (X = Br, I) salts as halogen sources. Instead of the free radical process, the control experiments indicate that the reported reactions proceed through a halogenium intermediate. Compared to the known synthetic methods relying on molecular halogen, haloid acid or N-halosuccinimide as the halogen source, the present method is attractive due to its higher atom economy and being more friendly to the operator, thus providing a practical complimentary approach to the preparation of useful halochromone compounds.