38445-23-7

Usage

Uses

Used in Pharmaceutical Industry:
6-Methylchromone is used as an active ingredient for the development of pharmaceutical drugs due to its antibacterial and antifungal properties. These properties contribute to the effectiveness of medications in treating various infections and diseases.
Used in Research Activities:
6-Methylchromone is utilized as a research compound in scientific studies, particularly in the fields of chemistry and biology. Its unique structure and properties make it an interesting subject for investigations into new drug development, understanding molecular interactions, and exploring potential applications in other industries.

Upstream product

• 68723-78-4 6-methyl-4-oxo-4H-chromene-3-carboxylic acid 
• 120-65-0 ortho-dimethylaminomethylphenol 
• 89807-39-6 (2E)-3-(dimethylamino)-1-(2-hydroxy-5-methylphenyl)-2-propen-1-one 
• 42059-81-4 3-formyl-6-methylchromone 
• 107-97-1 sarcosine 
• 16883-69-5 N-phenacylpyridinium bromide 

Downstream Products

• 68723-78-4 6-methyl-4-oxo-4H-chromene-3-carboxylic acid 
• 60630-08-2 N,N'-bis-<1-(2-hydroxy-5-methylphenyl)ethylidene>ethylenediamine 
• 90380-32-8 5-(2-hydroxy-5-methylphenyl)-2,3-dihydro-1,4-diazepine 
• 138163-20-9 N-<1-(2-hydroxy-5-methylphenyl)ethylidene>-N'-<2-(2-hydroxy-5-methylobenzoyl)vinylene>ethylenediamine 
• 90380-42-0 N,N'-bis<2-(2-hydroxy-5-methylbenzoyl)vinylene>ethylenediamine 
• 100421-16-7 (2-Hydroxy-5-methyl-phenyl)-pyrazolo[1,5-a]pyridin-3-yl-methanone 
• 123532-15-0 N₁-2-(2-hydroxy-5-methylbenzoyl)vinyl-N₁-methylhydrazine 
• 73484-69-2 6-methyl-3-hydroxychromone 
• 13252-83-0 4-hydroxy-6-methylcoumarin 
• 18385-83-6 6-methyl-2H-chromene 
• 685555-22-0 C₁₆H₁₀Cl₂O₂ 
• 29976-75-8 6-methylflavone 
• 3489-11-0 6-methylflavanone 

Relevant academic research and scientific papers

One-Pot Synthesis of B-Ring Ortho-Hydroxylated Sappanin-Type Homoisoflavonoids

A reliable method for the synthesis of B-ring hydroxylated homoisoflavonoids and 3-hetarylmethyl chromones has been developed. The method involves an initial oxa-Diels-Alder reaction of ortho-quinone methides generated from aryl/hetaryl-substituted ortho-(N,N-dimethylaminomethyl)phenols with (2E)-3-(N,N-dimethylamino)-1-(2-hydroxyphenyl)prop-2-en-1-ones and the subsequent cascade of reactions. This synthetic strategy avoids conventional multistep protocols and does not require the protection of hydroxyl groups, thus allowing the facile synthesis of a library of various aromatic and heterocyclic analogues of naturally occurring homoisoflavonoids.

Reaction of sarcosine with chromone-3-carbaldehyde and 6,6′- (polymethylenedioxy)di(chromone-3-carbaldehyde)

On treatment with N-methylglycine in DMF, the chromone-3-carbaldehydes 1a-c produce 3-[3-(2-hydroxybenzoyl)-1-methyl-2,5-dihydropyrrol-2-yl]-4H-chromen-4- ones 10a-c and the deformylated products 9a-c, whereas the bischromone derivatives 12a-c give the bis[3-(2-hydroxybenzoyl)-1-methylpyrrole] structures 13a-c.

Benzopyrans : Part 40 - Alumina mediated transformations of 4-oxo-4H-1- benzopyran-3-carbaldehyde, -3-carboxylic acid and their 2-methylhomologues

In contact with alumina, the title aldehyde 1 (R = H, Me, Cl) gives the chromones 5 and 9,12 whereas the acid 2 affords the chromones 7, 10 and acetophenone 23. Alumina converts the aldehyde 3 to the xanthone 14, and the corresponding acid 4 to the chromone 8 and diketone 24.

Benzopyrans: Part 34 - Reactions of 3-substituted 1-benzopyran-4-ones with N-phenacylpyridinium bromide

N-Phenacylpyridinium bromide in the presence of potassium carbonate gives the indolizine 10 and pyridinium salt 12 with the aldehyde 1 as well as the acid 2, azirine 14 with the nitrile 3, and zwitterion 16 with the ester 4. The pyridinium bromide 12 is converted into 10, and a mixture of 5 and 10 on refluxing in pyridine and dimethylformamide, respectively.