1026594-26-2

Basic information

• Product Name: (S)-4-(1-Benzyl-4-oxo-piperidin-3-yl)-2-benzyloxycarbonylamino-4-oxo-butyric acid
• CAS NO: 1026594-26-2
• Molecular Weight: 438.48
• Mol File: 1026594-26-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-4-(1-Benzyl-4-oxo-piperidin-3-yl)-2-benzyloxycarbonylamino-4-oxo-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-(1-Benzyl-4-oxo-piperidin-3-yl)-2-benzyloxycarbonylamino-4-oxo-butyric acid(1026594-26-2)
• EPA Substance Registry System: (S)-4-(1-Benzyl-4-oxo-piperidin-3-yl)-2-benzyloxycarbonylamino-4-oxo-butyric acid(1026594-26-2)

Safety Data

• Hazardous Substances Data: 1026594-26-2(Hazardous Substances Data)

Upstream product

• 109870-10-2 1,2,3,6-tetrahydro-1-(phenylmethyl)-4-[(trimethylsilyl)oxy]pyridine 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Downstream Products

• 1026046-87-6 [(S)-3-(1-Benzyl-4-oxo-piperidin-3-yl)-1-(2-tert-butoxycarbonylamino-ethylcarbamoyl)-3-oxo-propyl]-carbamic acid benzyl ester 

Relevant articles and documents

Design and asymmetric synthesis of β-strand peptidomimetics

We describe the asymmetric synthesis of non-peptidic compounds that feature rigid backbone conformations and present various side-chain functions. The key step in the synthesis of these compounds is the C-acylation of an appropriate ketone with a suitably protected aspartic acid derivative. The resulting dipeptide modules may be connected to form tetrapeptide mimics. Specifically is described the mimicry of a four-residue segment of CD4, the cellular receptor of HIV-1. The design was based on molecular modeling and the X-ray crystal structures of CD4 and intended to present the most important side chains and backbone elements of the Phe43-Lys46 segment.