1026741-19-4

Upstream product

• 173315-66-7 7-Fluoro-1-(4-fluoro-phenyl)-8-methyl-6-nitro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 
• 173315-57-6 ethyl 2-(2-chloro-4-fluoro-3-methyl-5-nitrobenzoyl)-3-(dimethylamino)acrylate 
• 173315-56-5 2-chloro-4-fluoro-3-methyl-5-nitrobenzoic acid 
• 173315-65-6 2-chloro-4-fluoro-3-methyl-5-nitrobenzoyl chloride 
• 443-83-4 2-chloro-6-fluorotoluene 
• 924-99-2 ethyl 3-(dimethylamino)acrylate 
• 109-01-3 1-methyl-piperazine 
• 1027145-27-2 1-(4-Fluoro-phenyl)-8-methyl-7-(4-methyl-piperazin-1-yl)-6-nitro-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Studies on 6-aminoquinolones: Synthesis and antibacterial evaluation of 6-amino-8-methylquinolones

The 6-aminoquinolone had previously been identified as a new class of quinolone antibacterial agents. To continue our structure-activity relationship (SAR) study in this series, novel 6-amino-8-methylquinolone derivatives have now been synthesized and eva