1026752-53-3

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 497065-79-9 (E)-(2R,3R)-2-Amino-3-(dimethyl-phenyl-silanyl)-hex-4-enoic acid methyl ester 
• 916914-97-1 (2S,5R,6R)-1-(2,2,2-trifluoroacetyl)-5-methyl-6-(4-bromophenyl)-1,2,5,6-tetrahydropyridine-2-carboxylic acid methyl ester 
• 916915-00-9 (2S,5R,6R)-6-(4-Bromo-phenyl)-5-methyl-1-(2,2,2-trifluoro-acetyl)-piperidine-2-carboxylic acid methyl ester 
• 118486-94-5 2-(tributylstannyl)furan 

Downstream Products

• 916914-47-1 (2S,5R,6R)-6-(4-(furan-2-yl)phenyl)-5-methylpiperidine-2-carboxylic acid 

Relevant academic research and scientific papers

Convergent synthesis of complex diketopiperazines derived from pipecolic acid scaffolds and parallel screening against GPCR targets

A convergent approach to highly functionalized diketopiperazines (DKPs) using enantioenriched pipecolic acids is described. Scandium triflate-catalyzed [4 + 2] aza-annulation was employed to produce stereochemically well-defined building blocks. A resin "