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2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide monohydrochloride, also known as Trimecaine hydrochloride, is a chemical compound with both local anesthetic and antiarrhythmic properties. It is characterized by its ability to block nerve conduction and stabilize cardiac rhythms, making it a versatile agent in medical applications.

1027-14-1

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1027-14-1 Usage

Uses

Used in Medical Applications:
Trimecaine hydrochloride is used as a local anesthetic for its ability to block nerve conduction, providing pain relief during medical procedures. It is particularly effective in situations where temporary loss of sensation is required.
Used in Cardiology:
As a cardiac antiarrhythmic, Trimecaine hydrochloride is utilized to stabilize cardiac rhythms and prevent irregular heartbeats. This makes it a valuable tool in managing conditions that affect heart function.
Used in Postoperative Pain Management:
Trimecaine hydrochloride is used in epidural postoperative analgesia, particularly after major urological procedures. It is often combined with other analgesics, such as morphine, to provide effective pain relief and improve patient recovery.
Used in Pharmaceutical Formulations:
Trimecaine hydrochloride can be found in various pharmaceutical formulations designed to target specific medical needs. Its dual action as a local anesthetic and antiarrhythmic makes it a versatile component in the development of new medications.

Check Digit Verification of cas no

The CAS Registry Mumber 1027-14-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,0,2 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1027-14:
(6*1)+(5*0)+(4*2)+(3*7)+(2*1)+(1*4)=41
41 % 10 = 1
So 1027-14-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H24N2O.ClH/c1-6-17(7-2)10-14(18)16-15-12(4)8-11(3)9-13(15)5;/h8-9H,6-7,10H2,1-5H3,(H,16,18);1H

1027-14-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(Diethylamino)-N-mesitylacetamide hydrochloride

1.2 Other means of identification

Product number -
Other names 2-(diethylamino)-N-(2,4,6-trimethylphenyl)acetamide,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1027-14-1 SDS

1027-14-1Downstream Products

1027-14-1Relevant academic research and scientific papers

One-pot production process of trimecaine hydrochloride

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Paragraph 0006; 0017-0019, (2020/04/22)

The invention discloses a one-pot production process of trimecaine hydrochloride. According to the method, s-trimethyl aniline, chloro-acetyl chloride and diethyl amine carry out reactions to obtain trimecaine hydrochloride. The liquid phase purity of the obtained trimecaine hydrochloride product is 99.9% or above, the molar yield reaches 90-95%, and the production method of trimecaine hydrochloride has the advantages of short production period, easy operation, low cost, high yield, and the like.

A hydrochloric acid three a kain production method (by machine translation)

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Paragraph 0022-0024, (2019/03/28)

The invention discloses a hydrochloric acid three a kain production method. The method adopts the raw materials are trimethyl aniline, chloroacetyl chloride, diethylamine to carry out the reaction, the product is obtained in the liquid phase purity of 99.9% or more, the total yield up to 90% or more. The hydrochloride of this invention three a kain production method with the production cycle is short, the operation is simple, low cost, high yield the advantages, in addition the production method intermediate solvent recovery can be applied mechanically, more security and environmental protection; and is suitable for industrial production. (by machine translation)

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