10270-11-8 Usage
General Description
1-(dimethylamino)-1H-pyrrole-2,5-dione is a chemical compound belonging to the class of pyrrole-2,5-dione derivatives. It is also known as DMAPD and is a yellow solid with a molecular formula of C7H9NO2. DMAPD is used in various chemical reactions as a catalyst, particularly in esterification and amidation reactions. It is also utilized in the synthesis of pharmaceuticals and agrochemicals. The compound is known for its ability to act as a nucleophile and form strong covalent bonds with other molecules, making it a valuable tool in organic synthesis. However, DMAPD should be handled with caution as it may be harmful if ingested or inhaled, and can cause irritation to the skin and eyes.
Check Digit Verification of cas no
The CAS Registry Mumber 10270-11-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,7 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 10270-11:
(7*1)+(6*0)+(5*2)+(4*7)+(3*0)+(2*1)+(1*1)=48
48 % 10 = 8
So 10270-11-8 is a valid CAS Registry Number.
10270-11-8Relevant articles and documents
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Rubinstein et al.
, p. 3372 (1971)
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Access to indoles via Diels-Alder reactions of 2-vinylpyrroles with maleimides
Noland, Wayland E.,Lanzatella, Nicholas P.,Venkatraman, Lakshmanan,Anderson, Nicholas F.,Gullickson, Glen C.
experimental part, p. 1154 - 1176 (2010/03/04)
(Chemical Equation Presented) Variously substituted 2-vinylpyrroles underwent an endo-addition [4+2] cycloaddition reaction with maleimides followed by a spontaneous highly diastereoselective (93-98% de) isomerization to give tetrahydroindoles in moderate to excellent yield. Treatment with activated MnO2 in refluxing toluene provided the corresponding indoles in moderate to good yield. This highly convergent methodology for formation of indoles is versatile and the starting materials are conveniently prepared.
