1027063-99-5Relevant academic research and scientific papers
Scaffold hopping with molecular field points: Identification of a cholecystokinin-2 (CCK2) receptor pharmacophore and its use in the design of a prototypical series of pyrrole- and imidazole-based CCK2 antagonists
Low, Caroline M. R.,Buck, Ildiko M.,Cooke, Tracey,Cushnir, Julia R.,Kalindjian, S. Barret,Kotecha, Atul,Pether, Michael J.,Shankley, Nigel P.,Vinter,Wright, Laurence
, p. 6790 - 6802 (2007/10/03)
A new molecular modeling approach has been used to derive a pharmacophore of the potent and selective cholecystokinin-2 (CCK2) receptor antagonist 5 (JB93182), based on features shared with two related series. The technique uses "field points"
