1027087-85-9

Basic information

• Product Name: 6-amino-4-(3-chloro-phenyl)-3-(4-dimethylamino-phenyl)-6'-morpholin-4-yl-[2,3']bipyridinyl-5-carbonitrile
• CAS NO: 1027087-85-9
• Molecular Weight: 511.026
• Mol File: 1027087-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-amino-4-(3-chloro-phenyl)-3-(4-dimethylamino-phenyl)-6'-morpholin-4-yl-[2,3']bipyridinyl-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 6-amino-4-(3-chloro-phenyl)-3-(4-dimethylamino-phenyl)-6'-morpholin-4-yl-[2,3']bipyridinyl-5-carbonitrile(1027087-85-9)
• EPA Substance Registry System: 6-amino-4-(3-chloro-phenyl)-3-(4-dimethylamino-phenyl)-6'-morpholin-4-yl-[2,3']bipyridinyl-5-carbonitrile(1027087-85-9)

Safety Data

• Hazardous Substances Data: 1027087-85-9(Hazardous Substances Data)

Upstream product

• 1027978-94-4 3-(6-chloro-pyridin-3-yl)-2-(4-dimethylamino-phenyl)-3-oxo-propionic acid ethyl ester 
• 1026404-43-2 1-(6-chloro-pyridin-3-yl)-2-(4-dimethylamino-phenyl)-ethanone 
• 17078-29-4 (4-dimethylaminophenyl)acetic acid ethyl ester 
• 58757-38-3 6-Chloronicotinoyl chloride 
• 2972-73-8 2-(3-chlorobenzylidene)malononitrile 
• 1026950-17-3 2-(4-dimethylamino-phenyl)-1-(6-morpholin-4-yl-pyridin-3-yl)-ethanone 

Relevant articles and documents

5,6,7-Trisubstituted 4-Aminopyrido[2,3-d]pyrimidines as Novel Inhibitors of Adenosine Kinase

The synthesis and structure-activity relationship of a series of 5,6,7-trisubstituted 4-aminopyrido[2,3-d]pyrimidines as novel nonnucleoside adenosine kinase inhibitors is described. A variety of alkyl, aryl, and heteroaryl substituents were found to be tolerated at the C5, C6, and C7 positions of the pyridopyrimidine core. These studies have led to the identification of analogues that are potent inhibitors of adenosine kinase with in vivo analgesic activity.