1027097-77-3

Basic information

• Product Name: C₂₀H₁₀Br₂O₃
• Synonyms: C₂₀H₁₀Br₂O₃
• CAS NO: 1027097-77-3
• Molecular Weight: 458.106
• Mol File: 1027097-77-3.mol

Chemical Properties

• CAS DataBase Reference: C₂₀H₁₀Br₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₁₀Br₂O₃(1027097-77-3)
• EPA Substance Registry System: C₂₀H₁₀Br₂O₃(1027097-77-3)

Safety Data

• Hazardous Substances Data: 1027097-77-3(Hazardous Substances Data)

Upstream product

• 615-58-7 2,4-dibromophenol 
• 55696-06-5 2-bromo-anthracene-1,4-dione 

Relevant articles and documents

Synthesis of a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives bearing anti-trypanosomal and anti-leishmanial activity

Taking advantage of the structural features of natural products showing anti-trypanosomatid activity, we designed and synthesized a small library of 2-phenoxy-1,4-naphthoquinone and 2-phenoxy-1,4-anthraquinone derivatives. The library was obtained following a parallel approach and using readily available synthons. All the derivatives showed inhibitory activity toward either Trypanosoma or Leishmania species, with 8, 10, and 16 being the most active compounds against Trypanosoma brucei rhodesiense, Leishmania donovani, and Trypanosoma cruzi cells (IC50 = 50 nM, IC50 = 0.28 μM, and IC50 = 1.26 μM, respectively).