1027198-51-1

Basic information

• Product Name: 1-[1-Ethoxy-1-(p-tolyl-trimethylsilanyloxy-methyl)-allyl]-1H-benzotriazole
• CAS NO: 1027198-51-1
• Molecular Weight: 395.577
• Mol File: 1027198-51-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[1-Ethoxy-1-(p-tolyl-trimethylsilanyloxy-methyl)-allyl]-1H-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1-Ethoxy-1-(p-tolyl-trimethylsilanyloxy-methyl)-allyl]-1H-benzotriazole(1027198-51-1)
• EPA Substance Registry System: 1-[1-Ethoxy-1-(p-tolyl-trimethylsilanyloxy-methyl)-allyl]-1H-benzotriazole(1027198-51-1)

Safety Data

• Hazardous Substances Data: 1027198-51-1(Hazardous Substances Data)

Upstream product

• 161607-20-1 3-(benzotriazol-1-yl)-3-ethoxy-1-propene 
• 75-77-4 chloro-trimethyl-silane 
• 301171-08-4 N-<1-Ethoxy-1-(α-hydroxy-p-methylbenzyl)allyl>benzotriazole 
• 104-87-0 4-methyl-benzaldehyde 

Relevant articles and documents

Novel Routes to Enol Ethers, Unsymmetrical Ketones, α-Bromoalkyl Ketones, 1,4-Diketones, 2-Ethoxy-2-cyclopenetenones, and α-Keto Enamines

Highly regioselectve SN2' reactions of adducts 6 (readily prepared by reactions of halides with the allyl anion 12 of 11) with Grignard reagents gave enol ethers 13, which were converted (in one-pot reactions from 11) into ketones 14 and α-bromoalkyl ketones 15 in good yields.The monoprotected 1,4-diketone derivative 16 (prepared by Michael addition of the allyl anion 12 with methyl vinyl ketone) was converted both into 1,4-diketones 18 and into protected γ-hydroxyalkyl ketone 20 by propenoyl, or to both functionalities.The allyl anion 12 with α-substituted acetic esters gave α-acylated adducts 24, which underwent in situ unfavored endo-trig cyclization upon treatment with NaH and secondary amines, to give 2-ethoxy-2-cyclopenetenones 27 and 28 and α-keto enamines 25 in good yield.The mechanism for the cyclization is discussed.