1027211-42-2Relevant academic research and scientific papers
Long-lived luminogenic probe for detection of RNA in a crude solution of living bacterial cells
Saneyoshi, Hisao,Ito, Yoshihiro,Abe, Hiroshi
, p. 13632 - 13635 (2013/10/01)
A pre-type sensitizer for a lanthanide complex on an oligonucleotide was successfully converted to a perfect final structure in a target DNA/RNA-templated reaction, without any chemical reagent or enzyme, under neutral conditions. The final form of the lanthanide-oligonucleotide provided a long-lived luminescence signal, appropriate for time-gated luminescence analysis and signal amplification. Target DNA/RNA-assisted time-gated luminescence analysis is a powerful tool for elimination of autofluorescence and detection of target RNA in living bacterial cells.
A FRET-based fluorogenic phosphine for live-cell imaging with the Staudinger ligation
Hangauer, Matthew J.,Bertozzi, Carolyn R.
, p. 2394 - 2397 (2008/12/23)
Azide imaging: A fluorogenic phosphine based on a FRET-quenching mechanism allows for live-cell imaging of azido sugars by the Staudinger ligation. This design strategy can accommodate numerous fluorophores and complementary quenchers, enabling extension to multi-color imaging. In the image shown, the nuclei are blue while the cell surfaces and Golgi are green. (Figure Presented).
