1027236-20-9Relevant articles and documents
Unexpected Product from the Dakin-West Reaction of N-Acylprolines using Trifluoroacetic Anhydride: A Novel Access to 5-Trifluoromethyloxazoles
Kawase, Masami,Miyamae, Hiroshi,Narita, Mariko,Kurihara, Teruo
, p. 859 - 862 (1993)
The base-catalyzed reaction of N-acylprolines with trifluoroacetic anhydride proceeds through mesoionic 1,3-oxazolium-5-olates followed by the pyrrolidine ring cleavage to afford the 5-trifluoromethyloxazoles in good yields.Key Words: N-acylproline; oxazo