Tetrahedron Letters p. 859 - 862 (1993)
Update date:2022-08-03
Topics:
Kawase, Masami
Miyamae, Hiroshi
Narita, Mariko
Kurihara, Teruo
The base-catalyzed reaction of N-acylprolines with trifluoroacetic anhydride proceeds through mesoionic 1,3-oxazolium-5-olates followed by the pyrrolidine ring cleavage to afford the 5-trifluoromethyloxazoles in good yields.Key Words: N-acylproline; oxazo
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