102735-71-7

Upstream product

• 65750-59-6 2-(4-nitrobenzyloxycarbonylamino)ethanethiol 
• 90694-08-9 (3S,4R)-3-<(R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4-<(phenylthiocarbonyl)methyl>-2-azetidinone 
• 97033-07-3 C₁₈H₃₀N₂O₅SSi₂ 
• 97033-08-4 Acetic acid (2R,3R)-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-1-trimethylsilanyl-azetidin-2-yl ester 
• 92133-37-4 [(2R,3S)-3-((R)-1-Hydroxy-ethyl)-4-oxo-azetidin-2-yl]-thioacetic acid S-[2-(4-nitro-benzyloxycarbonylamino)-ethyl] ester 
• 4457-32-3 4-nitrobenzyl chloroformate 
• 87392-18-5 <3S-<3α(S^*),4β>>-benzyl<3-(1-t-butyldimethylsilyloxyethyl)-2-azetidinone-4-yl>acetate 
• 86978-81-6 (3R,4R)-4-acetoxy-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-1-trimethylsilyl-2-azetidinone 
• 76335-76-7 (+/-)-4β-carboxymethyl-3α-<(1R^*)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one 
• 64066-71-3 (3S,4R)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-4-(2-oxoethyl)-2-oxoazetidine 
• 72789-82-3 (3S,4R)-4-(2,2-dimethoxyethyl)-3-[(1RS)-1-(p-nitrobenzyloxycarbonyloxy)ethyl]-2-oxoazetidine 
• 90628-97-0 3(S)-<1(R)-<(tert-butyldimethylsilyl)oxy>ethyl>-4(R)-<<<<2-<<(p-nitrobenzyloxy)carbonyl>amino>ethyl>thio>carbonyl>methyl>azetidin-2-one 
• 98076-60-9 t-butyl (2S,3S)-1-(4-methoxybenzyl)-3-<(R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4-oxo-2-azetidinecarboxylate 
• 98076-61-0 (2S,3S)-1-(4-methoxybenzyl)-3-<(R)-1-(p-nitrobenzyloxycarbonyloxy)ethyl>-4-oxo-2-azetidinecarboxylic acid 

Downstream Products

• 90629-18-8 {(2R,3S)-2-[2-(4-Nitro-benzyloxycarbonylamino)-ethylsulfanylcarbonylmethyl]-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid 4-nitro-benzyl ester 
• 78072-31-8 Hydroxy-{(2R,3S)-2-[2-(4-nitro-benzyloxycarbonylamino)-ethylsulfanylcarbonylmethyl]-3-[(R)-1-(4-nitro-benzyloxycarbonyloxy)-ethyl]-4-oxo-azetidin-1-yl}-acetic acid 4-nitro-benzyl ester 
• 78072-32-9 (+/-)-4α-<<2-(p-nitrobenzyloxycarbonylamino)ethylthio>carbonylmethyl>-3β-<(1R^*)-1(p-nitrobenzyloxycarbonyloxy)ethyl>-1-azetidin-2-one 
• 72778-09-7 N-<<(p-nitrobenzyl)oxy>carbonyl>-O-<<(p-nitrobenzyl)oxy>carbonyl>thienamycin p-nitrobenzyl ester 
• 92133-47-6 C₄₀H₄₆N₅O₁₈PS 

Relevant academic research and scientific papers

REACTION OF ACETOXYAZETIDINONES WITH TRIMETHYLSILYLACETYL THIOLESTERS: PREPARATION OF AZETIDINONE-THIOLESTER PRECURSORS TO CARBAPENEMS

Reaction of acetoxyazetidinones, 1 and 2, with trimethylsilylacetyl thiolesters 10 afforded azetidinone-thiolesters, 11 and 12, which are useful intermediates in the carbapenem synthesis.

AN EFFICIENT CARBAPENEM SYNTHESIS VIA AN INTRAMOLECULAR WITTIG REACTION OF NEW TRIALKOXYPHOSPHORANE-THIOLESTERS

New trialkoxyphosphorane-thiolesters 10, obtained by reaction of oxalimides 9 with trialkyl phosphite, were efficiently cyclized by an intramolecular Wittig reaction to give carbapenems 11.

Studies on the Syntheses of Heterocyclic Compounds. Part 877. An Alternative Synthesis of Protected (+/-)-Thienamycin and a Related Compound

An alternative total synthesis of protected (+/-)-thienamycin (2) and an analogue is described. (+/-)-4β-(2,2-Dimethoxyethyl)-3α-*)-1-(-nitrobenzyloxycarbonyloxy)ethyl>azetidin-2-one (5), prepared from isoxazoline derivatives (4), was conve