1027372-29-7Relevant academic research and scientific papers
Thromboxane receptor antagonism combined with thromboxane synthase inhibition. 4. 8-[[(4-chlorophenyl)sulfonyl]amino]-4-(3-(3- pyridinyl)propyl)octanoic acid and analogs
Bhagwat,Gude,Boswell,Contardo,Cohen,Dotson,Mathis,Lee,Furness,Zoganas
, p. 4373 - 4383 (2007/10/02)
The title compound (10a) and its analogs were synthesized and found to possess two activities, the inhibition of the biosynthesis of thromboxane A2 and antagonism of its receptors. The in vitro and in vivo profile of these compounds as thromboxane recepto
