41038-63-5Relevant academic research and scientific papers
(N-phthalimidoalkyl) piperidines useful as treatments for psychosis
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, (2008/06/13)
There is described novel (N-phthalimidoalkyl) piperidine compounds which exhibit selective sigma-receptor antagonism and therefore are useful in the treatment of physiological or drug induced psychosis and dyskinesia in a mammal. Also described are pharmaceutical compositions containing sigma selective compounds and methods of using these compositions for treating physiological or drug induced psychosis or dyskinesia in a mammal. Further provided are methods for preparing the compounds of this invention.
CERTAIN (ARYLSULFONAMIDO- AND IMIDAZOLYL-)-SUBSTITUTED CARBOXYLIC ACIDS AND DERIVATIVES THEREOF AND USE FOR SUPPRESSING THROMBOXANE ACTIVITY
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, (2008/06/13)
The present invention is concerned with compounds of formula I STR1 wherein A, B, M, R, Ar and Het are as defined in the specification, pharmaceutically acceptable ester and amide derivatives thereof; N-oxides thereof, tetrazole derivatives thereof, and s
(Arylsulfonamido- and pyridyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity
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, (2008/06/13)
Disclosed are the compounds of formula STR1 wherein A represents lower alkylene; B represents oxygen, sulfur, lower alkylene, lower alkylene interrupted by oxygen, sulfur, sulfinyl or sulfonyl, (oxy-, sulfinyl-, sulfonyl- or thio)-lower alkylene, lower al
On the mechanism of epoxidation of alkenes with hypochlorite, catalysed by manganese(III) tetraarylporphyrins
Made, A. W. van der,Nolte, R. J. M.,Drenth, W.
, p. 537 - 551 (2007/10/02)
A detailed mechanistic study of the epoxidation of alkenes by the cytochrome-P-450 model sodium hypochlorite/manganese(III) tetraarylporphyrin is presented.From the zero-order rate dependence on alkene concentration and low-temperature-trapping experiment
