1027385-44-9

Upstream product

• 305794-48-3 4-methylene-1'-(tert-butoxycarbonyl)-4'-cyano-1,4'-bipiperidine 
• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 148133-82-8 4-methylene piperidine 
• 438208-30-1 4-[(4-chloro-phenyl)-hydroxy-methyl]-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester 
• 305794-50-7 4-hydroxymethyl-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester 
• 305794-51-8 4-formyl-1'-(tert-butoxycarbonyl)-4'-methyl-1,4'-bipiperidine 
• 305794-49-4 4-methylene-1'-(tert-butoxycarbonyl)-4'-methyl-1,4'-bipiperidine 

Relevant academic research and scientific papers

Synthesis, SAR, and biological evaluation of oximino-piperidino-piperidine amides. 1. Orally bioavailable CCR5 receptor antagonists with potent anti-HIV activity

We previously reported the discovery of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1′-[(2,4-dimethyl-3 -pyridinyl)carbonyl]-4′-methyl-1,4′-bipipefidine N-oxide 1 (SCH 351125) as an orally bioavailable human CCR5 antagonist for the treatment of HIV-1 infec