1027525-81-0

Basic information

• Product Name: 4-(3-bromo-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester
• Synonyms: 4-(3-bromo-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester
• CAS NO: 1027525-81-0
• Molecular Weight: 451.447
• Mol File: 1027525-81-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(3-bromo-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-bromo-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(1027525-81-0)
• EPA Substance Registry System: 4-(3-bromo-benzyl)-4'-methyl-[1,4']bipiperidinyl-1'-carboxylic acid tert-butyl ester(1027525-81-0)

Safety Data

• Hazardous Substances Data: 1027525-81-0(Hazardous Substances Data)

Upstream product

• 591-18-4 1-Bromo-3-iodobenzene 
• 305794-49-4 4-methylene-1'-(tert-butoxycarbonyl)-4'-methyl-1,4'-bipiperidine 
• 305794-48-3 4-methylene-1'-(tert-butoxycarbonyl)-4'-cyano-1,4'-bipiperidine 
• 159635-49-1 tert-butyl 4-methylidenepiperidine-1-carboxylate 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 148133-82-8 4-methylene piperidine 

Relevant articles and documents

Synthesis, SAR, and biological evaluation of oximino-piperidino-piperidine amides. 1. Orally bioavailable CCR5 receptor antagonists with potent anti-HIV activity

We previously reported the discovery of 4-[(Z)-(4-bromophenyl)(ethoxyimino)methyl]-1′-[(2,4-dimethyl-3 -pyridinyl)carbonyl]-4′-methyl-1,4′-bipipefidine N-oxide 1 (SCH 351125) as an orally bioavailable human CCR5 antagonist for the treatment of HIV-1 infec