1027560-48-0

Basic information

• Product Name: 4-(4-Methoxycarbonyl-phenyl)-4H-pyridine-1-carboxylic acid ethyl ester
• CAS NO: 1027560-48-0
• Molecular Weight: 287.315
• Mol File: 1027560-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Methoxycarbonyl-phenyl)-4H-pyridine-1-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Methoxycarbonyl-phenyl)-4H-pyridine-1-carboxylic acid ethyl ester(1027560-48-0)
• EPA Substance Registry System: 4-(4-Methoxycarbonyl-phenyl)-4H-pyridine-1-carboxylic acid ethyl ester(1027560-48-0)

Safety Data

• Hazardous Substances Data: 1027560-48-0(Hazardous Substances Data)

Upstream product

• 619-44-3 methyl 4-iodobenzoate 
• 63755-30-6 N-ethoxycarbonylpyridinium chloride 
• 110-86-1 pyridine 

Downstream Products

• 106047-17-0 4-Pyridin-4-yl-benzoic acid methyl ester 

Relevant articles and documents

Regioselective Addition ofd Copper-Zinc Aryl Organometallic Reagents to 3-substituted Pyridinium Salts

A number of 3-substituted pyridinium salts are subjected to nucleophilic addition by copper-zinc aryl organometallic reagents.The adducts are oxidized subsequently to form the corresponding 4-arylpyridines.In all the cases 1,4-addition products are obtained predominantly.The regioselectivity can be rationalized according to the hard-soft acid-base principle.Calculations on both charge distributions and FMO coefficients indicate that these reactions may be classified on the basis of the type of soft acid-soft base reactions.The observed γ-attack complies very well with the orientation of the FMO coefficients as estimated by a semiempirical method.