1027563-72-9

Upstream product

• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 26828-48-8 2-allyl-2-methyl-1,3-cyclopentanedione 
• 160146-77-0 (1R,7aS)-1-Hydroxy-1-isopropenyl-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-80-5 (1S,7aR)-7a-Methyl-1-(2-methyl-[1,3]dioxolan-2-yl)-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-84-9 (1R,7aS)-1-Isopropenyl-1-methoxycarbonyloxy-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-81-6 (1S,4R,7aR)-7a-Methyl-1-(2-methyl-[1,3]dioxolan-2-yl)-2,4,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-79-2 (1S,7aR)-1-Acetyl-7a-methyl-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-75-8 (S)-7a-Methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 160146-87-2 7a-Methyl-1-oxo-2,3,5,6,7,7a-hexahydro-1H-indene-4-carboxylic acid allyl ester 
• 160146-76-9 6-methyl-6-(3-iodopropyl)-1,4,8,11-tetraoxadispiro[4.1.4.2]tridecane 
• 1026628-33-0 3-(6-Methyl-1,4,8,11-tetraoxa-dispiro[4.1.4.2]tridec-6-yl)-propan-1-ol 
• 98-88-4 benzoyl chloride 
• 70833-73-7 6-allyl-6-methyl-1,4,8,11-tetraoxadispiro[4.1.4.2]tridecane 
• 160146-85-0 Benzoic acid (1S,4R,7aR)-7a-methyl-1-(2-methyl-[1,3]dioxolan-2-yl)-2,4,5,6,7,7a-hexahydro-1H-inden-4-ylmethyl ester 

Relevant academic research and scientific papers

A new candidate for a properly substituted CD ring component of vitamin D3 via intramolecular asymmetric olefination of a 1,3-cyclopentanedione derivative

A highly diastereoselective synthesis of hydrindenone derivative 5 (98% de) was achieved via diastereotopic differentiation of 1,3-cyclopentanedione derivative 4 by intramolecular Horner-Emmons olefination. In addition, the compound 5 was converted to ketone 2, a new building block for 1α,25-dihydroxyvitamin D3 (1).