1027576-33-5Relevant academic research and scientific papers
Nonclassical 2,4-diamino-6-(aminomethyl)-5,6,7,8-tetrahydroquinazoline antifolates: Synthesis and biological activities
Gangjee,Zaveri,Kothare,Queener
, p. 3660 - 3668 (1995)
Twenty 6-substituted 2,4-diaminotetrahydroquinazolines were designed, synthesized, and biologically evaluated as novel nonclassical inhibitors of dihydrofolate reductase (DHFR) from Pneumocystis carinii and Toxoplasma gondii and as antitumor agents. The 6
