1027586-11-3Relevant academic research and scientific papers
Benzylic C-H trifluoromethylation of phenol derivatives
Egami, Hiromichi,Ide, Takafumi,Kawato, Yuji,Hamashima, Yoshitaka
, p. 16675 - 16678 (2015)
Phenol derivatives were trifluoromethylated using copper/Togni reagent. In dimethylformamide, the benzylic C-H bond at the para position of the hydroxyl group was selectively substituted with a CF3 group. In contrast, aromatic C-H trifluorometh
A new and efficient conversion of alkylphenols into the corresponding substituted salicylic acids
Katritzky,Lang,Lan
, p. 1175 - 1182 (2007/10/02)
A three-step sequence suitable for the synthesis of alkyl substituted salicylic acids from the corresponding alkylphenols involves ortho-directed lithiation of the methoxymethyl aryl ethers followed by quenching with carbon dioxide and deprotection under acidic conditions.
