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Upstream product

• 403-42-9 1-(4-fluorophenyl)ethanone 
• 147471-21-4 3-ethyl 1,5-dihydro-4-<4-(1H-imidazol-1-yl)-3-nitrophenyl>-2H-pyrrol-2-one 
• 115621-55-1 3-ethyl 4-(4-fluorophenyl)-1,5-dihydro-1-(4-methoxyphenyl)-2H-pyrrol-2-one 
• 115621-59-5 3-ethyl-4-(4-fluoro-3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one 
• 115653-72-0 4-(4-fluorophenyl)-1,5-dihydro-1-(4-methoxyphenyl)-2H-pyrrol-2-one 
• 115621-57-3 3-ethyl-4-(4-fluorophenyl)-1,5-dihydro-2H-pyrrol-2-one 
• 147471-19-0 (E)-3-(4-fluorophenyl)-2-butenoic acid ethyl ester 

Relevant academic research and scientific papers

(Imidazolylphenyl)pyrrol-2-one inhibitors of cardiac cAMP phosphodiesterase

Seven 3-alkyl-4-aryl-1,5-dihydro-2H-pyrrol-2-ones were prepared as potential inhibitors of cardiac cAMP phosphodiesterase (PDE). The design of these compounds made use of rolipram, a known inhibitor of the brain cAMP PDE isozyme, as a lead structure and w

Cardiotonic imidazolylphenylpyrrol-2-ones

Novel imidazolylphenylpyrrol-2-ones are described as having cardiovascular properties especially as cardiotonic agents in the treatment of congestive heart failure. Pharmaceutical formulations containing such compounds are also described.