147471-19-0

Basic information

• Product Name: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID ETHYL ESTER
• Synonyms: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID ETHYL ESTER;ethyl (2E)-3-(4-fluorophenyl)but-2-enoate
• CAS NO: 147471-19-0
• Molecular Formula: C₁₂H₁₃FO₂
• Molecular Weight: 208.2288232
• Mol File: 147471-19-0.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID ETHYL ESTER(147471-19-0)
• EPA Substance Registry System: (E)-3-(4-FLUORO-PHENYL)-BUT-2-ENOIC ACID ETHYL ESTER(147471-19-0)

Safety Data

• Hazardous Substances Data: 147471-19-0(Hazardous Substances Data)

Usage

General Description

(E)-3-(4-fluoro-phenyl)-but-2-enoic acid ethyl ester is a chemical compound that belongs to the class of butenoic acid esters. It is derived from the ethyl ester of (E)-3-(4-fluoro-phenyl)-but-2-enoic acid, which is a compound used in organic synthesis and pharmaceutical research. This chemical is commonly used in the development of new drugs and in the study of biological processes. It has potential applications in the pharmaceutical industry as a precursor for the synthesis of various pharmaceutical compounds. Additionally, it can also be used in research and development as a reagent or intermediate for the synthesis of other organic compounds.

Upstream product

• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 403-42-9 1-(4-fluorophenyl)ethanone 
• 623-73-4 diazoacetic acid ethyl ester 
• 888039-38-1 (2E)-ethyl 3-chloro-2-iodobut-2-enoate 
• 1765-93-1 4-fluoroboronic acid 
• 623-70-1 ethyl (E)-crotonate 
• 352-34-1 4-fluoro-1-iodobenzene 
• 311-46-6 ethyl 2-(dimethoxyphosphoryl)acetate 

Downstream Products

• 1201-86-1 (E)-3-(4-fluorophenyl)but-2-enoic acid 
• 1381931-80-1 (Z)-3-(4-fluorophenyl)but-2-en-1-ol 
• 132533-08-5 (E)-3-(4-fluorophenyl)but-2-en-1-ol 
• 1027034-10-1 (E)-3-(4-fluorophenyl)but-2-enal 
• 1376710-76-7 (E)-3-(4-fluorophenyl)-N-methoxy-N-methylbut-2-enamide 
• 115621-63-1 3-ethyl 1,5-dihydro-4-<4-(2-methyl-1H-imidazol-1-yl)-3-nitrophenyl>-2H-pyrrol-2-one 
• 115621-61-9 1,5-dihydro-3-methyl-4-<4-(2-methyl-1H-imidazol-1-yl)-3-nitrophenyl>-2H-pyrrol-2-one 
• 147471-21-4 3-ethyl 1,5-dihydro-4-<4-(1H-imidazol-1-yl)-3-nitrophenyl>-2H-pyrrol-2-one 

Relevant articles and documents

Copper-Photocatalyzed Contra-Thermodynamic Isomerization of Polarized Alkenes

The contra-thermodynamic isomerization of α- and β-substituted cinnamate derivatives catalyzed by the Cu(OAc)2/rac-BINAP complex under blue light irradiation is reported. The use of an oxazolidinone template, which favored the complexation of the copper catalyst to the substrate, allowed the E → Z isomerization of the catalytically formed chromophore under simple and robust reaction conditions in good to excellent ratios. The mechanism of this process based on the transient formation of a chromophore was also studied.

Selective Synthesis of Z-Cinnamyl Ethers and Cinnamyl Alcohols through Visible Light-Promoted Photocatalytic E to Z Isomerization

A photocatalytic E to Z isomerization of alkenes using an iridium photosensitizer under mild reaction conditions is disclosed. This method provides scalable and efficient access to Z-cinnamyl ether and allylic alcohol derivatives in high yields with excellent stereoselectivity. Importantly, this method also provides a powerful strategy for the selective synthesis of Z-magnolol and honokiol derivatives possessing potential biological activity.

The synthesis of non-racemic β-alkyl-β-aryl-disubstituted allyl alcohols and their transformation into allylamines and amino acids bearing a quaternary stereocenter

A synthesis of non-racemic β-alkyl-β-aryl allyl alcohols and their transformation into allylamines bearing a quaternary stereogenic center is reported. The allyl alcohols were prepared either by Cu-catalyzed enantioselective reduction of enones or by sequ