1027936-13-5

Basic information

• Product Name: (Z)-(2R,5S)-6-Phenyl-2-propyl-4-trimethylsilanyloxy-5-(trityl-amino)-hex-3-enoic acid methyl ester
• CAS NO: 1027936-13-5
• Molecular Weight: 591.866
• Mol File: 1027936-13-5.mol

Chemical Properties

• CAS DataBase Reference: (Z)-(2R,5S)-6-Phenyl-2-propyl-4-trimethylsilanyloxy-5-(trityl-amino)-hex-3-enoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-(2R,5S)-6-Phenyl-2-propyl-4-trimethylsilanyloxy-5-(trityl-amino)-hex-3-enoic acid methyl ester(1027936-13-5)
• EPA Substance Registry System: (Z)-(2R,5S)-6-Phenyl-2-propyl-4-trimethylsilanyloxy-5-(trityl-amino)-hex-3-enoic acid methyl ester(1027936-13-5)

Safety Data

• Hazardous Substances Data: 1027936-13-5(Hazardous Substances Data)

Upstream product

• 210580-12-4 3-oxo-5-phenyl-4S-(tritylamino)pentanoic acid allyl ester 

Relevant articles and documents

A stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres

A simple, stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres has been developed. The method is short (6 steps) and diastereoselective (85-95% de) and enantioselective (>95% ee).

A stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres

A simple, stereocontrolled synthesis of monofluoro ketomethylene dipeptide isosteres has been developed. N-Tritylated ketomethylene dipeptide isosteres, prepared from N-tritylated amino acids, are converted to their Z- TMS enol ethers and fluorinated with Selectfluor. There is cooperative stereocontrol between the N-tritylamine group and the alkyl group at C-2. The method is short (six steps), diastereoselective (85 → 95%), and enantioselective (>95%).