1027993-17-4

Basic information

• Product Name: 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester
• Synonyms: 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester
• CAS NO: 1027993-17-4
• Molecular Weight: 335.444
• Mol File: 1027993-17-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(1027993-17-4)
• EPA Substance Registry System: 3-(Cyclohexylmethyl-amino)-4-(2,2-dimethoxy-ethyl)-benzoic acid methyl ester(1027993-17-4)

Safety Data

• Hazardous Substances Data: 1027993-17-4(Hazardous Substances Data)

Upstream product

• 146667-95-0 2,2-dimethoxy-1-(4-methoxycarbonyl-2-nitrophenyl)ethane 
• 104447-80-5 (E)-1-(dimethylamino)-2-[4-(methoxycarbonyl)-2-nitrophenyl]ethene 
• 96-98-0 4-methyl-3-nitrobenzoic acid 
• 167478-76-4 2-amino-4-carbomethoxy-phenylacetaldehyde dimethylacetal 
• 2043-61-0 cyclohexanecarbaldehyde 

Downstream Products

• 182345-37-5 1-cyclohexylmethyl-1H-indole-6-carboxylic acid methyl ester 

Relevant articles and documents

Convenient preparation of N-substituted indoles by modified Leimgruber-Batcho indole synthesis

A modified reductive alkylation of pre-indole 3, prepared from readily available Leimgruber-Batcho indole synthesis derived intermediates, followed by acidic methanolysis generates 6-carbomethoxy-N-substituted indoles. The three step preparation of pre-indole 3 from substituted 2-nitrotoluene 1 in 66% yield and conversion to a variety of N-substituted indoles is presented.