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CAS

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1027995-92-1

(4-Trifluoromethyl-phenyl)-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1027995-92-1 Structure

  • Basic information

    1. Product Name: (4-Trifluoromethyl-phenyl)-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester
    2. Synonyms:
    3. CAS NO:1027995-92-1
    4. Molecular Formula:
    5. Molecular Weight: 342.402
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1027995-92-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (4-Trifluoromethyl-phenyl)-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester(CAS DataBase Reference)
    10. NIST Chemistry Reference: (4-Trifluoromethyl-phenyl)-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester(1027995-92-1)
    11. EPA Substance Registry System: (4-Trifluoromethyl-phenyl)-acetic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester(1027995-92-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1027995-92-1(Hazardous Substances Data)

1027995-92-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1027995-92-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,7,9,9 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1027995-92:
(9*1)+(8*0)+(7*2)+(6*7)+(5*9)+(4*9)+(3*5)+(2*9)+(1*2)=181
181 % 10 = 1
So 1027995-92-1 is a valid CAS Registry Number.

1027995-92-1Relevant articles and documents

Presynaptic cholinergic modulators as potent cognition enhancers and analgesic drugs. 1. Tropic and 2-phenylpropionic acid esters

Gualtieri,Conti,Dei,Giovannoni,Nannucci,Romanelli,Scapecchi,Teodori,Fanfani,Ghelardini,Giotti,Bartolini

, p. 1704 - 1711 (2007/10/02)

Previous studies have shown that (R)-(+)-hyoscyamine has analgesic activity as a consequence of increased ACh release following antagonism of central muscarinic autoreceptors. Since the enhancement of central cholinergic transmission could be beneficial for cognitive disorders, we manipulated (R)-(+)-hyoscyamine, synthesizing several derivatives of tropic and 2-phenylpropionic acids, with the aim of obtaining drugs which are able to increase ACh release and consequently to show analgesic and nootropic activities. The results showed that several new compounds are indeed potent analgesics (with an analgesic efficacy comparable to that of morphine) and that the most potent one ((±)-19, PG9) also has remarkable cognition- enhancing properties. Our study confirmed that the mechanism of action involves ACh release even if it is still unclear whether only muscarinic autoreceptors or, also, heteroreceptors are involved.

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