10280-24-7Relevant academic research and scientific papers
Ribo-, Xylo-, and Arabino-configured adenine-based nucleoside phosphonates: Synthesis of monomers for solid-phase oligonucleotide assembly
Pav, Ondrej,Budesinsky, Milos,Rosenberg, Ivan
, p. 1053 - 1056 (2007/10/03)
Adenine-based, regioisomeric nucleoside phosphonates with ribo, xylo and arabino configuration were synthesized in the protected form suitable for the phosphotriester-like, solid-phase synthesis of oligonucleotides. Phosphonate moiety was protected by 4-m
SYNTHESIS OF 2'-END LIPOPHILIZED DERIVATIVES OF 2',5'-TRIADENYLATES
Pressova, Martina,Smrt, Jiri
, p. 487 - 497 (2007/10/02)
Synthesis of protected derivatives of 2 - 5 A3 core starting from 2',3'-O-ethoxymethylene-N6-benzoyladenosine (I) by triazolidate and/or modified triester method are described.Preparation of adenylyl-(2'-5')-adenylyl-(2'-5')-2',3'-O-(1-methoxyhexadecylidene)adenosine (X), adenylyl-(2'-5')-adenylyl-(2'-5')-2'(3')-O-palmitoyladenosine (XIII) and 5'-phosphoryladenyl-(2'-5')-adenylyl-(2'-5')-2',3'-O-(1-methoxyhexadecylidene)adenosine (XVI) are described.
