102818-54-2Relevant academic research and scientific papers
[18F] Fluorination of o-carborane via nucleophilic substitution: Towards a versatile platform for the preparation of 18F-labelled BNCT drug candidates
Gona, Kiran B.,Gomez-Vallejo, Vanessa,Padro, Daniel,Llop, Jordi
, p. 11491 - 11493 (2013)
The mono-[18F]fluorination of o-carborane via nucleophilic substitution is reported. The new radiochemical transformation uses cyclotron produced [18F]F- and a carboranyl iodonium salt. Further derivatization of the 18F-labelled carborane is achieved by formation of the Cc-lithio salt and reaction with an aldehyde.
