1028252-16-5 Usage
Uses
Used in Pharmaceutical Industry:
Cyclopropanecarboxamide, 1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1) is used as a reagent for the preparation of methoxyisoquinoline derivatives. These derivatives have shown potential in the development of new pharmaceutical compounds with various therapeutic applications.
Used in Hepatitis C Treatment:
In the field of antiviral drug development, Cyclopropanecarboxamide, 1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1) plays a crucial role in the synthesis of asunaprevir (BMS-650032). Asunaprevir is an orally efficacious NS3 protease inhibitor specifically designed for the treatment of hepatitis C virus (HCV) infection. The compound has demonstrated its effectiveness in inhibiting the replication of the virus, thereby helping to control and manage the disease in patients.
Used in Structure-Activity Relationship (SAR) Studies:
Cyclopropanecarboxamide, 1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1) is also employed in the field of medicinal chemistry for conducting structure-activity relationship (SAR) studies. These studies involve the systematic investigation of the relationship between the chemical structure of a series of compounds and their biological activities. By understanding these relationships, researchers can design and develop more effective and selective drugs with improved pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1028252-16-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,8,2,5 and 2 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1028252-16:
(9*1)+(8*0)+(7*2)+(6*8)+(5*2)+(4*5)+(3*2)+(2*1)+(1*6)=115
115 % 10 = 5
So 1028252-16-5 is a valid CAS Registry Number.
1028252-16-5Relevant academic research and scientific papers
Concise asymmetric synthesis of a (1R,2S)-1-amino-2- vinylcyclopropanecarboxylic acid-derived sulfonamide and ethyl ester
Lou, Sha,Cuniere, Nicolas,Su, Bao-Ning,Hobson, Lindsay A.
, p. 6796 - 6805 (2013/10/01)
The development and demonstration of short, robust and chromatography-free sequences for the preparation of a (1R,2S)-1-amino-2-vinylcyclopropane- carboxylic acid-derived sulfonamide and ethyl ester in ≥99% ee are described. Both compounds are common buil
