CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)

Base Information

Chemical Name:CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)
CAS No.:1028252-16-5
Molecular Formula:C₇H₈O₃S*C₉H₁₄N₂O₃S
Molecular Weight:402.492
Hs Code.:
Mol file:1028252-16-5.mol

Synonyms:(1R,2S)-1-amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide, p-toluenesulfonate salt

Suppliers and Price of CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide4-methylbenzenesulfonate
50mg
$ 305.00

Crysdot
(1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide4-methylbenzenesulfonate 95+%
250mg
$ 734.00

Chemenu
(1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide4-methylbenzenesulfonate(1:1) 95%
5g
$ 1094.00

Chemenu
(1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-ethenylcyclopropanecarboxamide4-methylbenzenesulfonate(1:1) 95%
1g
$ 365.00

Total 52 raw suppliers

Chemical Property of CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

(1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide4-methylbenzenesulfonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses (1R,2S)-1-Amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide 4-methylbenzenesulfonate acts as a reagent in the preparation, SAR of methoxyisoquinoline derivatives and discovery of asunaprevir (BMS-650032), an orally efficacious NS3 protease inhibitor for the treatment of hepatitis C virus infection.

Technology Process of CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1)

There total 4 articles about CyclopropanecarboxaMide, 1-aMino-N-(cyclopropylsulfonyl)-2-ethenyl-,(1R,2S)-, 4-Methylbenzenesulfonate(1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1459729-22-6
(1R,2S)-1-((E)-benzylideneamino)-2-vinylcyclopropane carboxamide

: 139631-62-2
cyclopropanesulfonyl chloride

: 1028252-16-5
(1R,2S)-1-amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide, p-toluenesulfonate salt

Guidance literature:: With toluene-4-sulfonic acid; In ethyl acetate; at 50 ℃; for 3.25h;
DOI:10.1039/c3ob41394b

Reference yield:

: 133038-44-5
[(benzylidene)amino]acetic acid ethyl ester

: 1028252-16-5
(1R,2S)-1-amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide, p-toluenesulfonate salt

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-[2,5-bis(trifluoromethyl)benzyl]cinchonidinium bromide / toluene / 0.25 h / 5 °C

1.2: 10 °C

2.1: formamide; sodium methylate / toluene; tetrahydrofuran; methanol / 4 h / 50 °C

3.1: toluene-4-sulfonic acid / ethyl acetate / 3.25 h / 50 °C

With N-[2,5-bis(trifluoromethyl)benzyl]cinchonidinium bromide; sodium methylate; toluene-4-sulfonic acid; formamide; In tetrahydrofuran; methanol; ethyl acetate; toluene;
DOI:10.1039/c3ob41394b

Reference yield:

: 169962-99-6
Benzylidene glycine amide

: 1028252-16-5
(1R,2S)-1-amino-N-(cyclopropylsulfonyl)-2-vinylcyclopropanecarboxamide, p-toluenesulfonate salt

Guidance literature:: Multi-step reaction with 2 steps

1.1: N-[2,5-bis(trifluoromethyl)benzyl]cinchonidinium bromide / toluene / 0.25 h / 5 °C

1.2: 10 °C

2.1: toluene-4-sulfonic acid / ethyl acetate / 3.25 h / 50 °C

With N-[2,5-bis(trifluoromethyl)benzyl]cinchonidinium bromide; toluene-4-sulfonic acid; In ethyl acetate; toluene;
DOI:10.1039/c3ob41394b