1028264-41-6

Basic information

• Product Name: 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester
• Synonyms: 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester
• CAS NO: 1028264-41-6
• Molecular Weight: 414.412
• Mol File: 1028264-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester(1028264-41-6)
• EPA Substance Registry System: 3-(3,4,5-trimethoxy-phenyl)-1a,2,3,8b-tetrahydro-1,5,7-trioxa-cyclopenta[g]cyclopropa[a]naphthalene-2-carboxylic acid methyl ester(1028264-41-6)

Safety Data

• Hazardous Substances Data: 1028264-41-6(Hazardous Substances Data)

Upstream product

• 581069-50-3 4-tert-butyl-2-naphtho[2,3-d][1,3]dioxol-6-yl-4,5-dihydro-oxazole 
• 581069-48-9 4-isopropyl-2-naphtho[2,3-d][1,3]dioxol-6-yl-4,5-dihydro-oxazole 
• 581069-45-6 6.7-Methylendioxy-1-<3.4.5-trimethoxy-phenyl>-1.2-dihydro-naphthoesaeure-(2)-methylester 
• 107401-98-9 Naphtho[2,3-d][1,3]dioxole-6-carbonitrile 
• 2675-79-8 1-bromo-3,4,5-trimethoxybenzene 

Downstream Products

• 4375-07-9 epipodophyllotoxin 
• 4375-06-8 epipicropodophyllotoxin 
• 173524-35-1 (-)-Methyl epipodophyllate 
• 581069-46-7 (5R,8S)-8-Hydroxy-5-(3,4,5-trimethoxy-phenyl)-5,8-dihydro-naphtho[2,3-d][1,3]dioxole-6-carboxylic acid methyl ester 

Relevant articles and documents

Efficient enantioselective total synthesis of (-)-epipodophyllotoxin

In only twelve steps the total synthesis of (-)-epipodophyllotoxin (2) has been completed starting from commercially available piperonal (1). The first stereo-center was formed under auxilary control, while the following epoxidation and radical cyclization proceeded with outstanding diastereoselectivity, which enabled the target molecule to be isolated in an overall yield of 30% and with 97% ee.