1028306-32-2

Upstream product

• 100-52-7 benzaldehyde 
• 252880-51-6 (4S,5S)-2-[1-Chloro-meth-(Z)-ylidene]-3-dibutylboranyl-4-methoxymethyl-5-phenyl-oxazolidine 
• 252880-50-5 (4S,5S)-3-(9-Bora-bicyclo[3.3.1]non-9-yl)-2-[1-chloro-meth-(Z)-ylidene]-4-methoxymethyl-5-phenyl-oxazolidine 
• 54623-66-4 (4S,5S)-(-)-2-chloromethyl-4-methoxymethyl-5-phenyl-2-oxazoline 

Relevant academic research and scientific papers

Azaenolates of 2-chloromethyl-4-methoxymethyl-5-phenyl-2-oxazoline - A highly diastereo- and enantioselective synthesis of oxazolinyloxiranes

The oxazoline-derived titanium azaenolate 6 couples highly stereoselectively with aldehydes affording highly optically pure oxazolinyloxiranes 7. The epoxide 7a has been deblocked to form the optically pure formyl oxirane 9. In contrast, the corresponding boron azaenolates 2 and 3 couple with very poor or no stereoselectivity. Lithium, aluminum and tin azaenolates have also been shortly studied.