1028481-96-0

Basic information

• Product Name: C₅₉H₈₂O₁₄
• Synonyms: C₅₉H₈₂O₁₄
• CAS NO: 1028481-96-0
• Molecular Weight: 1015.29
• Mol File: 1028481-96-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₅₉H₈₂O₁₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₉H₈₂O₁₄(1028481-96-0)
• EPA Substance Registry System: C₅₉H₈₂O₁₄(1028481-96-0)

Safety Data

• Hazardous Substances Data: 1028481-96-0(Hazardous Substances Data)

Upstream product

• 1028481-92-6 C₅₁H₆₈O₁₃ 
• 623-66-5 octanoic acid anhydride 

Relevant articles and documents

Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: Bryostatin look-alikes that mimic phorbol ester function

Highly potent bryostatin analogues which contain the complete bryostatin core structure have been synthesized using a pyran annulation approach as a key strategic element. The A ring pyran was assembled using a pyran annulation reaction between a C1-C8 hydroxy allylsilane and an aldehyde comprising C9-C13. This pyran was transformed to a new hydroxy allylsilane and then coupled with a preformed C ring aldehyde subunit in a second pyran annulation, with concomitant formation of the B ring. This tricyclic intermediate was elaborated to bryostatin analogues which displayed nanomolar to subnanomolar affinity for PKC, but displayed properties indistinguishable from a phorbol ester in a proliferation/attachment assay. Copyright