1029-23-8Relevant academic research and scientific papers
Method for synthesis of quinoline-8-amine and derivatives thereof from fluoroquinolines
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Page/Page column 5; 11, (2018/02/28)
The invention discloses a method for synthesis of quinoline-8-amine and derivatives thereof from fluoroquinolines, and belongs to the technical field of organic synthesis. The quinoline-8-amine and the derivatives thereof are prepared from fluoroquinoline compounds and aromatic amines compounds as a substrate in the presence of solvent toluene and hydrides by synthesizing reaction. The method is simple in operation and suitable for industrial production. The raw materials needed for the synthesis are cheap, the cost of the synthesis is low, and a variety of amino quinoline derivatives can be synthesized by the simple and single method.
Transition-metal-free site-selective C–F bond activation for synthesis of 8-aminoquinolines
Chen, Jianping,Huang, Dongyang,Ding, Yuqiang
, p. 4240 - 4242 (2017/10/10)
An efficient and general selective method for the synthesis of 8-aminoquinoline derivatives has been disclosed through transition metal direct C–N coupling from fluoroquinolines and arylamines. Significantly, good chemo- and regio-selectivity was observed
Triazine-based mesoporous covalent imine polymers as solid supports for copper-mediated chan-lam cross-coupling N-arylation reactions
Puthiaraj, Pillaiyar,Pitchumani, Kasi
, p. 8761 - 8770 (2014/07/21)
The synthesis of a novel mesoporous covalent imine polymeric (MCIPs) material, involving simple Schiff-base chemistry, is reported. This highly functionalised nitrogen-rich material acts as a good support for immobilising CuII ions, exhibiting excellent catalytic activity in promoting the Chan-Lam cross-coupling reaction between biologically active amines and arylboronic acids. The performance of this catalyst is also evident from its broad substrate scope, high stability, real heterogeneity, mild reaction conditions and reusability without loss of activity. The observed results will provide additional scope on the design and catalytic applications of this emerging class of materials.
