1029-96-5

Usage

Uses

Used in Pharmaceutical Industry:
2,6-Diphenyl-4H-thiopyran-4-one 96 is used as a pharmacophore model for the development of novel inhibitors of ubiquitin isopeptidases. These inhibitors have the potential to induce p53-independent cell death, which can be beneficial in the treatment of various diseases, including cancer.
Used in Dye Industry:
2,6-Diphenyl-4H-thiopyran-4-one 96 can also be utilized as a component in the synthesis of dyes. Its unique chemical structure and properties make it a valuable candidate for creating dyes with specific characteristics, such as color intensity, stability, and solubility.
Used in Metabolite Research:
In addition to its applications in the pharmaceutical and dye industries, 2,6-diphenyl-4H-thiopyran-4-one 96 can be employed in metabolite research. Its chemical properties and interactions with other molecules make it a promising candidate for studying metabolic pathways and identifying potential biomarkers for various diseases.

InChI:InChI=1/C17H12OS/c18-15-11-16(13-7-3-1-4-8-13)19-17(12-15)14-9-5-2-6-10-14/h1-12H

Upstream product

• 2168-78-7 methyl dithiobenzoate 
• 57094-07-2 2,6-diphenyl-4H-thiopyran 
• 37014-01-0 4-oxo-2,6-diphenyl-thiane 
• 536-74-3 phenylacetylene 
• 15814-32-1 1,5-diphenylpenta-1,4-diyn-3-ol 
• 15814-30-9 1,5-diphenyl-penta-1,4-diyn-3-one 
• 83258-48-4 (Z)-1-Ethoxy-1,5-diphenyl-pent-1-en-4-yn-3-one 
• 35225-79-7 dibenzylideneacetone 

Downstream Products

• 13895-58-4 4-(2,6-diphenyl-4H-thiopyran-4-ylidene)-2-phenyloxazol-5(4H)-one 
• 960384-58-1 [(CO)5W(C(OCH₃)CHC₅H₂S(C₆H₅)2)] 
• 1029-97-6 2,6-diphenyl-4H-thiopyran-4-thione 
• 103225-50-9 2,2',6,6'-tetraphenyl-Δ^4,4'-bithiopyran 1,1,1',1'-tetraoxide 
• 103225-46-3 4-((dimethoxyphosphinyl)methyl)-2,6-diphenyl-4-hydroxy-4H-thiopyran 1,1-dioxide 
• 97671-88-0 2,6-diphenyl-4-(1,3-dioxoindan-2-ylidene)-4H-thiopyran 1,1-dioxide 
• 97671-92-6 2,6-diphenyl-4-(cyano(ethoxycarbonyl)methylene)-4H-thiopyran 1,1-dioxide 
• 103225-45-2 2,6-diphenyl-4-hydroxy-4-methyl-4H-thiopyran 1,1-dioxide 
• 103225-51-0 2,2',6,6'-teraphenyl-Δ^4,4'-bithiopyran 1,1-dioxide 
• 97671-87-9 2,6-diphenyl-4-(2,2-dimethyl-4,6-dioxo-m-dioxan-5-ylidene)-4H-thiopyran 1,1-dioxide 

Relevant academic research and scientific papers

Oxidation reactions of 4H-chalcogenopyrans

We have studied the oxidation of 4H-chalcogenopyrans and chalcogenopyrylium salts by lead tetraacetate. We have established that the major reaction products on oxidation of 2,6-diphenyl-4H-thiopyran and selenopyran are 2,6-diphenyl-4H-thio(seleno)pyran-4-

Substituted sulfur aromatic heterocyclic compound, preparation method and application thereof

The present invention provides a sulfur aromatic heterocyclic compound represented by a formula I, and an optical isomer thereof, wherein Y is an anion, R1 is NR4R5, hydrogen, halogen, a C1-C4 alkyl group, a C1-C4 alkoxy group, a trifluoromethoxy group

Chalcogenopyranones from disodium chalcogenide additions to 1,4- pentadiyn-3-ones. The role of enol ethers as intermediates

Enol ethers 9 are formed as a mixture of E- and Z-isomers from the addition of ethanol to 1,4-pentadiyn-3-ones 2 in sodium ethoxide/ethanol. The enol ethers react with disodium chalcogenides to give the corresponding 2,6- disubstituted chalcogenopyranones

The reaction of unsaturated carbonyl compounds with "activated" sulfur

In a reinvestigation of the sulfuration reaction of cinnamylideneacetophenone (1) with sulfur and triethylamine at room temperature, new products 6-benzoyl-3-phenyl-1,2-dithiolo1,2-dithiole (5), 6-benzoyl-3-phenyl-1,2-dithiine (6) and 5-benzoyl-3-b

Synthesis of 2,6-Diaryl-4H-thiopyran-4-ones

A novel synthesis of 2,6-diaryl-4H-thiopyran-4-ones has been developed.The title compounds were prepared by two sequential thio-Claisen condensations of a dialkyl ketone and two dithioesters.The intermediate β-thioxo ketone from the first condensation was converted to the corresponding β-(methylthio)enone for both protection and reactivity purposes.Facile addition-elimination of the methylthio moiety by a β-thioxo ketone enolate generated in the second thio-Claisen condensation afforded the desired heterocycle.This new method is rapid and simple with the only requirement being moderate substituent alkaline stability.

THE OXIDATION REACTIONS OF THIOPYRANS

A method was developed for the preparation of compounds with 4H-thiopyrone structure by the oxidation of the corresponding 4H-thiopyranes and their condensed analogs by potassium permanganate.