10290-98-9 Usage
Description
2,6-Dichlorobenzenesulfonamide, a member of the sulfonamide class, is a white crystalline solid with the molecular formula C6H5Cl2NO2S. It is widely recognized for its use as an antibacterial agent and an inhibitor of the enzyme carbonic anhydrase. This chemical compound has been the subject of research for its potential antitumor and antiviral activities and is utilized as a reagent in organic synthesis.
Uses
Used in Pharmaceutical Synthesis:
2,6-Dichlorobenzenesulfonamide is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique chemical properties make it a valuable component in the development of new medications.
Used in Agrochemical Production:
In the agrochemical industry, 2,6-Dichlorobenzenesulfonamide is utilized as a precursor in the production of various agrochemicals. Its application contributes to the development of effective pest control agents and other agricultural products.
Used in Dye Manufacturing:
2,6-DICHLOROBENZENESULFONAMIDE is also employed in the manufacturing of dyes, where its chemical structure imparts specific color characteristics to the final product.
Used in Organic Synthesis as a Reagent:
2,6-Dichlorobenzenesulfonamide serves as a reagent in organic synthesis, facilitating various chemical reactions and contributing to the formation of desired products in organic chemistry.
Used in Research for Antitumor and Antiviral Activities:
2,6-Dichlorobenzenesulfonamide is under investigation for its potential as an antitumor and antiviral agent. Its ability to inhibit certain biological processes makes it a candidate for further study in the development of treatments for cancer and viral infections.
Safety Consideration:
Check Digit Verification of cas no
The CAS Registry Mumber 10290-98-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,2,9 and 0 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 10290-98:
(7*1)+(6*0)+(5*2)+(4*9)+(3*0)+(2*9)+(1*8)=79
79 % 10 = 9
So 10290-98-9 is a valid CAS Registry Number.
10290-98-9Relevant articles and documents
N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase
Lehr, Philipp,Billich, Andreas,Wolff, Barbara,Nussbaumer, Peter
, p. 1235 - 1238 (2005)
Steroid sulfatase (STS) is an attractive target for a range of oestrogen- and androgen-dependent diseases. In search of novel chemotypes of STS inhibitors, we had previously identified nortropinyl-arylsulfonylureas 1; however, while these compounds were good inhibitors of purified STS (lowest Ki = 76 nM), they showed only weak inhibition of STS activity in cells (lowest IC50 around 2 μM). Extended structure-activity relationship studies involving modification of the phenylacetyl side chain and replacement of the nortropine element by simpler scaffolds led to the discovery of N-acyl arylsulfonamides, more specifically N-(Boc-piperidine-4-carbonyl)- benzenesulfonamides, as STS inhibitors, some of which exhibit improved cellular potency (best IC50 = 270 nM).
NAPHTHALENE AND QUINOLINE SULFONYLUREA DERIVATIVES AS EP4 RECEPTOR ANTAGONISTS
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Page/Page column 27-28, (2008/12/04)
The invention is directed to naphthalene and quinoline sulfonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, osteoarthritis, rheumatoid arthritis and cancer. Pharmaceutical compositions and methods of use are also included.
Il-8 receptor antagonists
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, (2008/06/13)
This invention relates to novel compounds of Formula (I) to (VII), and compositions thereof, useful in the treatment of disease states mediated by the chemokine, Interleukin-8 (IL-8).
