1029061-05-9Relevant articles and documents
Efficient synthesis and biological evaluation of proximicins A, B and C
Brucoli, Federico,Natoli, Antonino,Marimuthu, Preethi,Borrello, Maria Teresa,Stapleton, Paul,Gibbons, Simon,Sch?tzlein, Andreas
, p. 2019 - 2024 (2012)
A quick and efficient synthesis and the biological evaluation of promising antitumor-antibiotics proximicins A, B and C are reported. The characteristic repetitive unit of these molecules, the methyl 4-Boc-aminofuran-2-carboxylate 15, was prepared in thre
Total synthesis of proximicin A - C and synthesis of new furan-based DNA binding agents
Wolter, Falko E.,Schneider, Kathrin,Davies, Brian P.,Socher, Elke R.,Nicholson, Graeme,Seitz, Oliver,Suessmuth, Roderich D.
supporting information; experimental part, p. 2804 - 2807 (2009/12/05)
The total synthesis of the natural occurring polyamides proximicin A-C (3-5) has been accomplished. A short and efficient synthesis of a thus far unknown 4-amino-2-furan carboxylic acid was developed. Furthermore, this unique heterocyclic γ-amino-acid was