1029124-38-6

Basic information

• Product Name: (E)-2-(2-methoxy-phenyl)-1-nitro-propene
• Synonyms: (E)-2-(2-methoxy-phenyl)-1-nitro-propene
• CAS NO: 1029124-38-6
• Molecular Weight: 193.202
• Mol File: 1029124-38-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (E)-2-(2-methoxy-phenyl)-1-nitro-propene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-2-(2-methoxy-phenyl)-1-nitro-propene(1029124-38-6)
• EPA Substance Registry System: (E)-2-(2-methoxy-phenyl)-1-nitro-propene(1029124-38-6)

Safety Data

• Hazardous Substances Data: 1029124-38-6(Hazardous Substances Data)

Upstream product

• 10278-02-1 2-(2-methoxyphenyl)propene 
• 579-74-8 2-Methoxyacetophenone 

Downstream Products

• 1029124-44-4 2-(2-methoxyphenyl)-1-nitropropane 
• 1253909-36-2 (R)-1-methoxy-2-(1-nitropropan-2-yl)benzene 

Relevant articles and documents

Water-Enabled Catalytic Asymmetric Michael Reactions of Unreactive Nitroalkenes: One-Pot Synthesis of Chiral GABA-Analogs with All-Carbon Quaternary Stereogenic Centers

Water enables new catalytic reactions for otherwise unreactive substrate systems. Under the “on water” reaction conditions, extremely unreactive β,β-disubstituted nitroalkenes smoothly underwent enantioselective Michael addition reactions with dithiomalonates using a chiral squaramide catalyst, affording both enantiomers of highly enantioenriched Michael adducts with all-carbon-substituted quaternary centers. The developed “on water” protocol was successfully applied for the scalable one-pot syntheses of chiral GABA analogs with all-carbon quaternary stereogenic centers at the β-position, which might show highly interesting pharmaceutical properties.

Rh-catalyzed highly enantioselective hydrogenation of nitroalkenes under basic conditions

Go catalytic! A highly enantioselective hydrogenation of β,β-disubstituted nitroalkenes and isomeric mixtures of nitroalkenes by using a Rh/DuanPhos catalytic system under basic conditions has furnished a convenient approach to β-chiral nitroalkanes, whic