102950-52-7Relevant articles and documents
The effect of the nitrogen non-bonding electron pair on the NMR and X-ray in 1,3-diazaheterocycles
Garcías-Morales, Cesar,Martínez-Salas, Selene H.,Ariza-Castolo, Armando
supporting information; experimental part, p. 3310 - 3315 (2012/08/08)
The effect of the nitrogen nonbonding electron pair on the 1JC,H values of 1,3-diazaheterocycles was analyzed and compared to 1,5-diazabiciclo[3.2.1]octanes, which have a restricted conformation. The 1JC,H values were measured by observing the 13C satellites in the 1H NMR spectra and then determining the 1H-coupled 13C NMR spectra. The 1JC,H values are 10 Hz larger when the α-hydrogen is synperiplanar rather than antiperiplanar to the nonbonding electron pair on the nitrogen, which serves as experimental evidence of the orbital n N→σC,Hap interactions. In addition, the homoanomeric effect from the interactions of the nitrogen lone pair with the antibonding orbital of the equatorial hydrogen, which was in the β position, was discussed (nN→σC(β),H eq).
Reversible formation of aminals: A new strategy to control the release of bioactive volatiles from dynamic mixtures
Godin, Guillaume,Levrand, Barbara,Trachsel, Alain,Lehn, Jean-Marie,Herrmann, Andreas
experimental part, p. 3125 - 3127 (2010/08/21)
Dynamic mixtures generated by reversible aminal formation of fragrance aldehydes with N,N′-dibenzyl alkyldiamines in aqueous systems were found to be suitable delivery systems for the controlled release of bioactive volatiles. The Royal Society of Chemistry 2010.
Preparation of aminals in water
Jur?ík, Václav,Wilhelm, René
, p. 3205 - 3210 (2007/10/03)
Aminals, which are used as protecting groups in syntheses and are part of many biologically active compounds, are normally prepared from aldehydes and diamines under conditions that remove water in order to shift the equilibrium to the side of the aminal.