102988-75-0Relevant academic research and scientific papers
4,5-bis(aryl) 4H-1,2,4-triazoles derivatives and analgesic use
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, (2008/06/13)
A novel process for the preparation of 4H-1,2,4-triazoles in their racemic or optically active forms of the formula STR1 wherein the compounds have analgesic activity.
Synthesis and analgesic activity in 1,2,4-triazole series
Clemence,Joliveau-Maushart,Meier,et al.
, p. 257 - 266 (2007/10/02)
Derivatives of 1,2,4-triazole have been synthesized. Several methods of synthesis were used and the analgetic and antiinflammatory properties of the products obtained were studied. Structural requirements for analgetic activity were specified. Certain compounds show a high degree of analgetic activity. One of them, RU 39813, has been chosen for extended pharmacological study.
