102990-14-7

Basic information

• Product Name: Benzenemethanol, 4-chloro-a-(phenylethynyl)-
• CAS NO: 102990-14-7
• Molecular Formula: C15H11ClO
• Molecular Weight: 242.705
• Mol File: 102990-14-7.mol
• Article Data: 56

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 4-chloro-a-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 4-chloro-a-(phenylethynyl)-(102990-14-7)
• EPA Substance Registry System: Benzenemethanol, 4-chloro-a-(phenylethynyl)-(102990-14-7)

Safety Data

• Hazardous Substances Data: 102990-14-7(Hazardous Substances Data)

Upstream product

• 932-88-7 1-iodo-2-phenylethyne 
• 104-88-1 4-chlorobenzaldehyde 
• 536-74-3 phenylacetylene 
• 28995-88-2 1-methyl-4-((phenylethynyl)sulfonyl)benzene 
• 4440-01-1 lithium phenylacetylide 
• 7335-27-5 ethyl 4-chlorobenzoate 
• 1178514-34-5 C₁₇H₁₅ClO₂ 
• 675825-21-5 Lithium enolate of the acetaldehyde 

Downstream Products

• 875877-83-1 [[1-(4-chlorophenyl)-3-phenyl-2-propynyl]oxy]-trimethylsilane 
• 1228390-79-1 2-(1-(4-chlorophenyl)-3-phenylprop-2-ynyl)-1,3,5-trimethoxybenzene 
• 1228390-78-0 1-chloro-4-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)benzene 
• 1262587-78-9 ethyl 2-[(ethoxycarbonyl)amino]-3-[1-(4-chlorophenyl)-3-phenylprop-2-ynyl]-1H-indole-1-carboxylate 
• 1359755-47-7 N-[1-(4-chlorophenyl)-3-phenyl-2-propyn-1-yl]-4-methylbenzenesulfonamide 
• 1379594-88-3 2-(1-(4-chlorophenyl)-3-phenylprop-2-ynyl)thiophene 
• 1421675-08-2 3,6-bis(1-(4-chlorophenyl)-3-phenylprop-2-ynyl)-9-methyl-9H-carbazole 
• 1265166-74-2 ethyl 1-(4-chlorophenyl)-2-methyl-4-(4-chlorophenyl)-5-benzyl-1H-pyrrole-3-carboxylate 
• 1198104-41-4 3-(1-(4-chlorophenyl)-3-phenylprop-2-ynyl)-4-hydroxy-2H-coumarin 
• 1266366-06-6 1-(4-chlorophenyl)-2,3-diiodo-1H-indene 
• 1263296-54-3 methyl 2-acetyl-3-(4-chlorophenyl)-5-phenylpent-4-ynoate 
• 1263296-55-4 ethyl 2-acetyl-3-(4-chlorophenyl)-5-phenylpent-4-ynoate 
• 1261266-55-0 (+/-)-ethyl (E)-3-[1-(4-chlorophenyl)-3-phenylprop-2-ynyloxy]acrylate 

Relevant articles and documents

A straightforward, efficient and versatile preparation of propargylic alcohols from 1-alkynes and aldehydes via GaI3 and amine

The straightforward additions of 1-alkynes to aldehydes in the presence of GaI3 and an amine give propargylic alcohol in moderate to high yields.

Visible Light-Induced Reductive Alkynylation of Aldehydes by Umpolung Approach

Reductive alkynylation of aldehydes by the Umpolung approach was developed using a photoredox catalyst under blue LED irradiation. Ketyl radicals, generated by single-electron reduction of aldehydes through proton-coupled electron transfer (PCET), reacted with electrophilic alkynylsulfones. Sterically demanding bulky aldehydes reacted smoothly under the Umpolung reaction conditions. Moreover, the alkynylation proceeded chemoselectively with an aryl aldehyde group in the presence of other carbonyl groups including an aliphatic aldehyde group.

Straightforward Stereoselective Synthesis of Seven-Membered Oxa-Bridged Rings through in Situ Generated Cycloheptenol Derivatives

An iodine-mediated stereoselective synthesis of seven-membered oxa-bridged rings via in situ generated cycloheptenols was reported. This process was realized through the combination of C-C σ-bond cleavage and C-O bond-forming reactions in a one-pot fashion from simple and easily accessible raw materials. The formation of carbon radicals initiated by I2 was the key to the reaction.

HighlyZ-selective synthesis of 1,3-oxathiol-2-ylidenes and 4-methylene-oxazolidine-2-thionesviaatom-specific 5-exo-digcyclization of propargyl alcohol with isothiocyanate

DBU mediated 5-exo-digcyclization of isothiocyanate and propargyl alcohol leading to valuable heterocyclic compounds has been accomplished. The different modes of nucleophilicity (eitherS-selective orN-selective) of isothiocyanates were found to depend on