28995-88-2Relevant academic research and scientific papers
A facile access to mono-C-alkynylated-o-carboranes from o-carboranes and arylsulfonylacetylenes
Bai, Mengyang,Tao, Guanyu,Liu, Zhenxing,Wang, Lili,Duan, Zheng
supporting information, p. 201 - 204 (2021/06/27)
A facile access to mono-C-alkynyl-o-carboranes from o-carboranes and arylsulfonylacetylenes was developed. This facile process tolerates a wide variety of functional groups, occurs at mild conditions in one-pot procedure with short reaction time. The obtained mono-C-alkynyl-o-carboranes can be easily derivatized to synthesize 1,2-difunctionalized o-carboranes. This work provides a useful tool for the functionalization of o-carboranes.
Radical-mediated sulfonyl alkynylation, allylation, and cyanation of propellane
Wu, Zhen,Xu, Yaohui,Zhang, Huihui,Wu, Xinxin,Zhu, Chen
, p. 6066 - 6069 (2021/06/21)
Bicyclo[1.1.1]pentane (BCP) is widely applied as the bioisostere for aryl, internal alkynes, andtert-butyl groups in medicinal chemistry. We herein disclose an efficient and practical preparation of sulfonyl alkynyl/allyl/cyano-substituted BCP derivatives
Direct and Efficient Synthesis of Sulfonium Acyl Sulfonylmethylide Ylides from Acetylenic Sulfones and Dimethyl Sulfoxide
Fu, Duo,Wang, Jiayi,Xu, Jiaxi
, p. 4086 - 4096 (2021/08/10)
Bifunctionalized sulfonium ylides - sulfonium acyl sulfonylmethylides - were directly and efficiently prepared from various acetylenic sulfones and aliphatic sulfoxides under heating conditions. The current method features short reaction time, low cost, readily available starting materials, convenient operation, and purification, providing an efficient access to widely applied bifunctionalized sulfonium ylides.
Decatungstate as Direct Hydrogen Atom Transfer Photocatalyst for SOMOphilic Alkynylation
Capaldo, Luca,Ravelli, Davide
, p. 2243 - 2247 (2021/04/05)
A versatile approach for the alkynylation of a variety of aliphatic hydrogen donors, including alkanes, is reported. We used tetrabutylammonium decatungstate as photocatalyst to generate organoradicals from C-H/Si-H bonds via hydrogen atom transfer. The l
An iodine-mediated new avenue to sulfonylation employingN-hydroxy aryl sulfonamide as a sulfonylating agent
Raghuvanshi, Dushyant Singh,Verma, Narsingh
supporting information, p. 4760 - 4767 (2021/06/09)
A novel and highly efficient I2/K2CO3mediated regioselective sulfonylation of thiophenols, aryl acetylenic acid and aromatic alkynes withN-hydroxy sulfonamide has been developed.N-hydroxy sulfonamide has been used for the first time for the synthesis of these sulfones. The scope and versatility of the reaction has been demonstrated by the regio- and stereoselective synthesis of different analogs of sulfones with various structural features.
Pd-Catalyzed Annulation of β-Iodovinyl Sulfones with 2-Halophenols: A General Route for the Synthesis of 3-Sulfonyl Benzofuran Derivatives
Krishna, Gamidi Rama,Kumar, Jangam Jagadesh,Kumari, Arram Haritha,Reddy, Raju Jannapu
, (2020/03/04)
The palladium-catalyzed annulation between β-iodovinyl sulfones and 2-halophenols or 1-bromo-2-naphthol or 2-bromo-3-pyridinol is presented. The annulation process involving oxa-Michael addition-elimination and intramolecular Heck reaction leading to form
Electrochemically enabled sulfonylation of alkynes with sodium sulfinates
Meng, Xiangtai,Xu, Hehua,Cao, Xiaoji,Cai, Xu-Min,Luo, Jinyue,Wang, Fei,Huang, Shenlin
supporting information, p. 6827 - 6831 (2020/09/15)
An electrochemical sulfonylation of alkynes with sodium sulfinates was achieved for the first time at room temperature. Employing this electrolysis strategy, the reaction occurs efficiently under transition-metal-free, external oxidant-free, and base-free conditions and furnishes diverse alkynyl sulfones in satisfactory yield with broad functional group tolerance.
Alkynyl sulfone compound as well as preparation method and application thereof
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Paragraph 0043-0050; 0079-0082; 0085-0092; 0098-0102, (2021/03/06)
The invention relates to the technical field of chemical synthesis, and particularly discloses an alkynyl sulfone compound and a preparation method and application thereof, and the alkynyl sulfone compound comprises the following raw materials: an alkyne
Oxidative Addition of Alkenyl and Alkynyl Iodides to a AuI Complex
Bower, John F.,Cadge, Jamie A.,Russell, Christopher A.,Sparkes, Hazel A.
supporting information, p. 6617 - 6621 (2020/03/13)
The first isolated examples of intermolecular oxidative addition of alkenyl and alkynyl iodides to AuI are reported. Using a 5,5′-difluoro-2,2′-bipyridyl ligated complex, oxidative addition of geometrically defined alkenyl iodides occurs readily, reversibly and stereospecifically to give alkenyl-AuIII complexes. Conversely, reversible alkynyl iodide oxidative addition generates bimetallic complexes containing both AuIII and AuI centers. Stoichiometric studies show that both new initiation modes can form the basis for the development of C?C bond forming cross-couplings.
Electrochemical decarboxylative sulfonylation of arylacetylenic acids with sodium arylsulfinates: Access to arylacetylenic sulfones
Zhong, Qihao,Zhao, Yongli,Sheng, Shouri,Chen, Junmin
supporting information, p. 161 - 167 (2019/12/03)
An efficient decarboxylative sulfonylation of arylacetylenic acids with sodium arylsulfinates has been achieved by an electro-oxidative strategy. This novel protocol offers a simple, efficient, and green route to a series of arylacetylenic sulfones in mod
