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CAS

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103059-55-8

2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 103059-55-8 Structure

  • Basic information

    1. Product Name: 2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol
    2. Synonyms: 2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol
    3. CAS NO:103059-55-8
    4. Molecular Formula:
    5. Molecular Weight: 298.342
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 103059-55-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol(103059-55-8)
    11. EPA Substance Registry System: 2-(3,4-Dimethoxy-benzyl)-7-methyl-1H-benzoimidazol-4-ol(103059-55-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 103059-55-8(Hazardous Substances Data)

103059-55-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 103059-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,0,5 and 9 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 103059-55:
(8*1)+(7*0)+(6*3)+(5*0)+(4*5)+(3*9)+(2*5)+(1*5)=88
88 % 10 = 8
So 103059-55-8 is a valid CAS Registry Number.

103059-55-8Downstream Products

103059-55-8Relevant articles and documents

Novel 1H-Benzimidazol-4-ols with Potent 5-Lipoxygenase Inhibitory Activity

Buckle, Derek R.,Foster, Keith A.,Taylor, John F.,Tedder, John M.,Thody, Veronica E.,et al.

, p. 2216 - 2221 (2007/10/02)

The synthesis and structure-activity profile of 2-substituted benzimidazol-4-ols as inhibitors of cell-free RBL-1 5-lipoxygenase are discussed, and their potency is compared with that of the standard inhibitors phenidone, AA 861, BW 755C, and nordihydroguaiaretic acid.In contrast to the standard comounds, most did not inhibit the release of slow-reacting substance of anaphylaxis (SRS-A) in vivo when administered at 200 μM ip to rats subjected to peritoneal anaphylaxis, although five compounds containing a methoxylated benzyl group (compounds 36, 39, 42, and 43) or hydroxylated benzyl group (41) showed similar activity to that of phenidone, nordihydroguaiaretic acid, and AA 861.Of the many compounds tested, two, 5-tert-butyl-7-methyl-2-(trifluoromethyl)-1H-benzimidazol-4-ol (57) and 2-(4-methoxybenzyl)-7-methyl-1H-benzimidazol-4-ol (36), like dexamethasone, inhibited monocyte accumulation in a pleural exudate model of inflammation.Standard lipoxygenase inhibitors such as phenidone, BW 755C, and AA 861 were inactive in this system.

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