103112-02-3

Basic information

• Product Name: 3-bromo-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one
• CAS NO: 103112-02-3
• Molecular Weight: 358.256
• Mol File: 103112-02-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-bromo-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-bromo-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one(103112-02-3)
• EPA Substance Registry System: 3-bromo-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one(103112-02-3)

Safety Data

• Hazardous Substances Data: 103112-02-3(Hazardous Substances Data)

Upstream product

• 22118-09-8 2-bromoacetyl chloride 
• 103112-01-2 N-glycine ethyl ester 

Relevant articles and documents

Electrochemical Studies on β-Lactams. Part 1. Electroreduction of 3-Halogeno-β-lactams

The electrochemical reduction in aprotic solvents of 3-halogeno-β-lactams (1a-c) and (2a-c), with or without added proton donors or/and electrophiles, has been investigated.Without added substrates, the carbanion arising from the cleavage of the carbon-halogen bond undergoes protonation (mainly from the 'parent'molecule) and, completely, ring-opening reactions yielding the corresponding dehalogenated β-lactam and α,β-unsaturated amide.In the presence of proton donors (CH3CO2H) or electrophiles (CO2), the protonation and coupling reactions, respectively, become largely predominant, and the dehalogenated or carboxylated β-lactams are the main products.In the presence of BrCH2CH2CN the protonation reaction is preferred, and the dehalogenated β-lactam predominates over the substitution product.The high yields of 3-carboxy-β-lactams, a class of compounds not easily accessible by chemical methods, are noteworthy from a synthetic point of view.