103112-01-2

Upstream product

• 87386-07-0 N-(thiobenzoyl)glycine ethyl ester 
• 420-37-1 trimethoxonium tetrafluoroborate 
• 98-88-4 benzoyl chloride 
• 1499-53-2 ethyl hippurate 

Downstream Products

• 103112-04-5 3,3-dichloro-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one 
• 161198-41-0 ethyl 2,5-diphenyl-4-thiazolecarboxylate 
• 64951-84-4 ethyl trans-4,5-dihydro-2,5-diphenyl-4-oxazolecarboxylate 
• 64951-84-4 ethyl cis-4,5-dihydro-2,5-diphenyl-4-oxazolecarboxylate 
• 93729-29-4 ethyl 2,5-diphenyloxazole-4-carboxylate 
• 15926-46-2 diethyl 2-phenyl-4,5-oxazoledicarboxylate 
• 134857-33-3 2-ethyl 3,4-dimethyl 5-phenyl-1H-pyrrole-2,3,4-tricarboxylate 
• 103112-05-6 1-ethoxycarbonylmethyl-4-methylthio-3-phenoxy-4-phenylazetidin-2-one 
• 103112-03-4 3-chloro-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one 
• 103112-02-3 3-bromo-1-ethoxycarbonylmethyl-4-methylthio-4-phenylazetidin-2-one 

Relevant academic research and scientific papers

Synthesis of oxazoles and thiazoles using thioimidates

Several oxazoles and thiazoles were synthesized easily by the reaction of N-(methylthioalkylidene)glycine ethyl ester with diethyl oxalate, acid halides, and thionesters in the presence of base.

Transformation of Alkyl N-(Vinyloxy)benzimidates to Alkyloxazoles. Mechanism and Extension

Transformation of alkyl N-(vinyloxy)benzimidates to alkyloxazoles proceeds through the intermediates: a charge-separated 1,2-oxazetidine derivative and then 1-hydroxy-2-imino>maleic acid diester, while their photochemical transformation takes place via a concerted sigmatropic shift.As the extension of this reaction, the preparation of the precursor proposed for virginiamycin M2 synthesis and the reaction of N-analogs of alkyl N-(vinyloxy)benzimidates are described.