1031282-20-8Relevant academic research and scientific papers
Synthesis of a new class of C2-symmetrical biheteroaryls by ammonium cerium(IV) nitrate mediated dimerization of 2-(furan-3-yl)pyrroles
Alcaide, Benito,Almendros, Pedro,Carrascosa, Rocio,Rosario Torres
supporting information; experimental part, p. 823 - 826 (2010/04/02)
Polyfunctionalized 2-(furan-2-yl)pyrroles and 2-(furan-3-yl)pyrroles derived from 2-azetidinone-tethered alienes by two independent cerium(IV)-mediated single-electron oxidations provided a (4-oxopent-2-enoyl) pyrrole and 3,3′-bis(pyrrol-2-yl)-2, 2′-bifurans, respectively. Access to the oxidation precursors was achieved by regiocontrolled cyclization of β-allenamine intermediates derived from selective β-lactam nucleus breakage of 2-azetidinone-tethered allenols.
New regiocontrolled synthesis of functionalized pyrroles from 2-azetidinone-tethered allenols
Alcaide, Benito,Almendros, Pedro,Carrascosa, Rocio,Redondo, Maria C.
, p. 637 - 643 (2008/12/21)
A new one-pot approach to synthesize densely substituted racemic and enantiopure pyrroles from β-lactams has been developed. The approach relies on the regiocontrolled cyclization of β-allenamine intermediates derived from the ring opening of 2-azetidinon
