10314-91-7

Basic information

• Product Name: (13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione
• Synonyms: (13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione
• CAS NO: 10314-91-7
• Molecular Formula: C26H34 O6
• Molecular Weight: 442.5446
• Mol File: 10314-91-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 588°Cat760mmHg
• Flash Point: 309.4°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 1.13E-14mmHg at 25°C
• Refractive Index: 1.586
• CAS DataBase Reference: (13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione(10314-91-7)
• EPA Substance Registry System: (13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione(10314-91-7)

Safety Data

• Hazardous Substances Data: 10314-91-7(Hazardous Substances Data)

Usage

General Description

The chemical compound "(13α,17aα)-14β,15β:21,23-Diepoxy-7α-hydroxy-4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione" is a complex steroid derivative. It is characterized by its unique structure, which includes a 14β,15β-epoxy group, a 17α-hydroxy group, and a 4,4,8-trimethyl-17-oxa-D-homo-24-nor-5α-chola-20,22-diene-3,16-dione backbone. These structural features give the compound its distinct biological activity and potential pharmacological properties. It may have implications in the fields of medicine, biochemistry, and pharmaceutical research, as it could potentially exhibit a range of biological effects. Further studies are needed to fully understand its potential applications and mechanisms of action.

InChI:InChI=1/C26H34O6/c1-22(2)16-12-18(28)25(5)15(23(16,3)9-7-17(22)27)6-10-24(4)19(14-8-11-30-13-14)31-21(29)20-26(24,25)32-20/h8,11,13,15-16,18-20,28H,6-7,9-10,12H2,1-5H3

Upstream product

• 13072-74-7 7-deacetoxy-7-oxogedunin 
• 10314-90-6 7-epi-deacetylgedunin 

Relevant articles and documents

The Synthesis of a 1α,2α,3α-Triacetoxy Limonoid

The report that Meerwein-Ponndorf reduction of gedunin (1a) gives 3α-hydroxy-3-deoxogedunin (2a) is wrong; the product is the 3β-epimer (2b). 3α-Acetoxy-7-deacetoxy-3-deoxo-7-oxgedunin (3c) was prepared by a stereospecific synthesis from cedrolide (1b), 7-deacetoxy-7-oxogedunin; osmium tetroxide oxidation then gave the 1,2α-glycol, isolated as the acetate (4a).Similarly, oxidation of the 3β-alcohol (3b) also gave the α-oriented glycol, as anticipated from the steric hindrance of the β-face of the molecule.Oxidation of the allylic alcohols (2b) or (3b), or of the allylic acetate (2d) with perbenzoic acid also takes place from the α-face of the molecule, giving the corresponding α-oxides (5a-c).The oxidation is pH sensitive; with a benzoate buffer the 7-oxo group in alcohol (3b) undergoes Baeyer-Villiger oxidation, giving the ε-lactone isolated as the acetate (6a).Opening of the oxide ring in the 3β,7α-diacetoxy oxide (5c) is complex.Identification of the products shows that the reaction involves participation by both the acetate groups.In contrast the 3β-acetoxy-7-oxo compound (5d) and the ε-lactone (6a) give the products of ring opening with assistance from the neighbouring acetate group, while the 3β-hydroxy compound (5b) gives the simple bromohydrin.